High GPR56 surface expression correlates with a leukemic stem cell gene signature in CD34‐positive AML

High GPR56 surface expression correlates with a leukemic stem cell gene signature in CD34‐positive AML

Abstract Acute myeloid leukemia (AML) is driven by a minor fraction of leukemic stem cells (LSCs) whose persistence is considered being the primary cause of disease relapse. A detailed characterization of the surface immunophenotype of LSCs to discriminate them from bulk leukemic blasts may enable s...

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Bibliographic Details
Main Authors: Shruti Daga, Angelika Rosenberger, Franz Quehenberger, Nina Krisper, Barbara Prietl, Andreas Reinisch, Armin Zebisch, Heinz Sill, Albert Wölfler
Format: Article
Language:English
Published: Wiley 2019-04-01
Series:Cancer Medicine
Subjects:
acute myeloid leukemia
CLL‐1
gene expression signature
GPR56
leukemic stem cells
Online Access:https://doi.org/10.1002/cam4.2053

Internet

https://doi.org/10.1002/cam4.2053

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