High GPR56 surface expression correlates with a leukemic stem cell gene signature in CD34‐positive AML
Abstract Acute myeloid leukemia (AML) is driven by a minor fraction of leukemic stem cells (LSCs) whose persistence is considered being the primary cause of disease relapse. A detailed characterization of the surface immunophenotype of LSCs to discriminate them from bulk leukemic blasts may enable s...
Main Authors: | Shruti Daga, Angelika Rosenberger, Franz Quehenberger, Nina Krisper, Barbara Prietl, Andreas Reinisch, Armin Zebisch, Heinz Sill, Albert Wölfler |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-04-01
|
Series: | Cancer Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/cam4.2053 |
Similar Items
-
Role of ADGRG1/GPR56 in Tumor Progression
by: Kwai-Fong Ng, et al.
Published: (2021-11-01) -
Adhesion GPCR GPR56 Expression Profiling in Human Tissues
by: Fyn Kaiser, et al.
Published: (2021-12-01) -
The Novel Immune Checkpoint GPR56 Is Expressed on Tumor-Infiltrating Lymphocytes and Selectively Upregulated upon TCR Signaling
by: Vrouyr Bilemjian, et al.
Published: (2022-06-01) -
Transcriptomics and Phenotypic Analysis of <i>gpr56</i> Knockout in Zebrafish
by: Luning Sun, et al.
Published: (2023-04-01) -
The Inhibitory Receptor GPR56 (<i>Adgrg1</i>) Is Specifically Expressed by Tissue-Resident Memory T Cells in Mice But Dispensable for Their Differentiation and Function In Vivo
by: Cheng-Chih Hsiao, et al.
Published: (2021-10-01)