Whole-genome sequencing reveals the molecular implications of the stepwise progression of lung adenocarcinoma

Whole-genome sequencing reveals the molecular implications of the stepwise progression of lung adenocarcinoma

Abstract The mechanism underlying the development of tumors, particularly at early stages, still remains mostly elusive. Here, we report whole-genome long and short read sequencing analysis of 76 lung cancers, focusing on very early-stage lung adenocarcinomas such as adenocarcinoma in situ (AIS) and...

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Main Authors: Yasuhiko Haga, Yoshitaka Sakamoto, Keiko Kajiya, Hitomi Kawai, Miho Oka, Noriko Motoi, Masayuki Shirasawa, Masaya Yotsukura, Shun-Ichi Watanabe, Miyuki Arai, Junko Zenkoh, Kouya Shiraishi, Masahide Seki, Akinori Kanai, Yuichi Shiraishi, Yasushi Yatabe, Daisuke Matsubara, Yutaka Suzuki, Masayuki Noguchi, Takashi Kohno, Ayako Suzuki
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43732-y

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