The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals
Abstract Background The United Arab Emirates (UAE) is faced with a rapidly increasing burden of non-communicable diseases including obesity, diabetes, and cardiovascular disease. The UAE Healthy Future study is a prospective cohort designed to identify associations between risk factors and these dis...
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| Format: | Article |
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BMC
2018-01-01
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| Series: | BMC Public Health |
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| Online Access: | http://link.springer.com/article/10.1186/s12889-017-5012-2 |
| _version_ | 1828768389202444288 |
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| author | Abdishakur Abdulle Abdullah Alnaeemi Abdullah Aljunaibi Abdulrahman Al Ali Khaled Al Saedi Eiman Al Zaabi Naima Oumeziane Marina Al Bastaki Mohammed Al-Houqani Fatma Al Maskari Ayesha Al Dhaheri Syed M. Shah Tom Loney Mohamed El-Sadig Abderrahim Oulhaj Leila Abdel Wareth Wael Al Mahmeed Habiba Alsafar Benjamin Hirsch Fatme Al Anouti Jamila Yaaqoub Claire K. Inman Aisha Al Hamiz Ayesha Al Hosani Muna Haji Teeb Alsharid Thekra Al Zaabi Fatima Al Maisary Divya Galani Tim Sprosen Omar El Shahawy Jiyoung Ahn Tomas Kirchhoff Ravichandran Ramasamy Ann Marie Schmidt Richard Hayes Scott Sherman Raghib Ali |
| author_facet | Abdishakur Abdulle Abdullah Alnaeemi Abdullah Aljunaibi Abdulrahman Al Ali Khaled Al Saedi Eiman Al Zaabi Naima Oumeziane Marina Al Bastaki Mohammed Al-Houqani Fatma Al Maskari Ayesha Al Dhaheri Syed M. Shah Tom Loney Mohamed El-Sadig Abderrahim Oulhaj Leila Abdel Wareth Wael Al Mahmeed Habiba Alsafar Benjamin Hirsch Fatme Al Anouti Jamila Yaaqoub Claire K. Inman Aisha Al Hamiz Ayesha Al Hosani Muna Haji Teeb Alsharid Thekra Al Zaabi Fatima Al Maisary Divya Galani Tim Sprosen Omar El Shahawy Jiyoung Ahn Tomas Kirchhoff Ravichandran Ramasamy Ann Marie Schmidt Richard Hayes Scott Sherman Raghib Ali |
| author_sort | Abdishakur Abdulle |
| collection | DOAJ |
| description | Abstract Background The United Arab Emirates (UAE) is faced with a rapidly increasing burden of non-communicable diseases including obesity, diabetes, and cardiovascular disease. The UAE Healthy Future study is a prospective cohort designed to identify associations between risk factors and these diseases amongst Emiratis. The study will enroll 20,000 UAE nationals aged ≥18 years. Environmental and genetic risk factors will be characterized and participants will be followed for future disease events. As this was the first time a prospective cohort study was being planned in the UAE, a pilot study was conducted in 2015 with the primary aim of establishing the feasibility of conducting the study. Other objectives were to evaluate the implementation of the main study protocols, and to build adequate capacity to conduct advanced clinical laboratory analyses. Methods Seven hundred sixty nine UAE nationals aged ≥18 years were invited to participate voluntarily in the pilot study. Participants signed an informed consent, completed a detailed questionnaire, provided random blood, urine, and mouthwash samples and were assessed for a series of clinical measures. All specimens were transported to the New York University Abu Dhabi laboratories where samples were processed and analyzed for routine chemistry and hematology. Plasma, serum, and a small whole blood sample for DNA extraction were aliquoted and stored at −80 °C for future analyses. Results Overall, 517 Emirati men and women agreed to participate (68% response rate). Of the total participants, 495 (95.0%), 430 (82.2%), and 492 (94.4%), completed the questionnaire, physical measurements, and provided biological samples, respectively. Conclusions The pilot study demonstrated the feasibility of recruitment and completion of the study protocols for the first large-scale cohort study designed to identify emerging risk factors for the major non-communicable diseases in the region. |
| first_indexed | 2024-12-11T13:28:21Z |
| format | Article |
| id | doaj.art-04de67feb82240fe8cdcdea22468480c |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-12-11T13:28:21Z |
| publishDate | 2018-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-04de67feb82240fe8cdcdea22468480c2022-12-22T01:05:23ZengBMCBMC Public Health1471-24582018-01-011811910.1186/s12889-017-5012-2The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationalsAbdishakur Abdulle0Abdullah Alnaeemi1Abdullah Aljunaibi2Abdulrahman Al Ali3Khaled Al Saedi4Eiman Al Zaabi5Naima Oumeziane6Marina Al Bastaki7Mohammed Al-Houqani8Fatma Al Maskari9Ayesha Al Dhaheri10Syed M. Shah11Tom Loney12Mohamed El-Sadig13Abderrahim Oulhaj14Leila Abdel Wareth15Wael Al Mahmeed16Habiba Alsafar17Benjamin Hirsch18Fatme Al Anouti19Jamila Yaaqoub20Claire K. Inman21Aisha Al Hamiz22Ayesha Al Hosani23Muna Haji24Teeb Alsharid25Thekra Al Zaabi26Fatima Al Maisary27Divya Galani28Tim Sprosen29Omar El Shahawy30Jiyoung Ahn31Tomas Kirchhoff32Ravichandran Ramasamy33Ann Marie Schmidt34Richard Hayes35Scott Sherman36Raghib Ali37New York University Abu DhabiZayed Military HospitalZayed Military HospitalZayed Military HospitalZayed Military HospitalSheikh Khalifa Medical CitySheikh Khalifa Medical CitySheikh Khalifa Medical CityUAE UniversityUAE UniversityUAE UniversityUAE UniversityUAE UniversityUAE UniversityUAE UniversityCleveland Clinic Abu DhabiCleveland Clinic Abu DhabiKhalifa University of Science Technology & ResearchKhalifa University of Science Technology & ResearchZayed UniversityAbu Dhabi Police Medical ServicesNew York University Abu DhabiNew York University Abu DhabiNew York University Abu DhabiNew York University Abu DhabiNew York University Abu DhabiNew York University Abu DhabiNew York University Abu DhabiNew York University Abu DhabiUniversity of OxfordNew York University School of MedicineNew York University School of MedicineNew York University School of MedicineNew York University School of MedicineNew York University School of MedicineNew York University School of MedicineNew York University School of MedicineNew York University Abu DhabiAbstract Background The United Arab Emirates (UAE) is faced with a rapidly increasing burden of non-communicable diseases including obesity, diabetes, and cardiovascular disease. The UAE Healthy Future study is a prospective cohort designed to identify associations between risk factors and these diseases amongst Emiratis. The study will enroll 20,000 UAE nationals aged ≥18 years. Environmental and genetic risk factors will be characterized and participants will be followed for future disease events. As this was the first time a prospective cohort study was being planned in the UAE, a pilot study was conducted in 2015 with the primary aim of establishing the feasibility of conducting the study. Other objectives were to evaluate the implementation of the main study protocols, and to build adequate capacity to conduct advanced clinical laboratory analyses. Methods Seven hundred sixty nine UAE nationals aged ≥18 years were invited to participate voluntarily in the pilot study. Participants signed an informed consent, completed a detailed questionnaire, provided random blood, urine, and mouthwash samples and were assessed for a series of clinical measures. All specimens were transported to the New York University Abu Dhabi laboratories where samples were processed and analyzed for routine chemistry and hematology. Plasma, serum, and a small whole blood sample for DNA extraction were aliquoted and stored at −80 °C for future analyses. Results Overall, 517 Emirati men and women agreed to participate (68% response rate). Of the total participants, 495 (95.0%), 430 (82.2%), and 492 (94.4%), completed the questionnaire, physical measurements, and provided biological samples, respectively. Conclusions The pilot study demonstrated the feasibility of recruitment and completion of the study protocols for the first large-scale cohort study designed to identify emerging risk factors for the major non-communicable diseases in the region.http://link.springer.com/article/10.1186/s12889-017-5012-2AdultChronic diseaseCohort studiesPilot projectsProspective studiesPublic health |
| spellingShingle | Abdishakur Abdulle Abdullah Alnaeemi Abdullah Aljunaibi Abdulrahman Al Ali Khaled Al Saedi Eiman Al Zaabi Naima Oumeziane Marina Al Bastaki Mohammed Al-Houqani Fatma Al Maskari Ayesha Al Dhaheri Syed M. Shah Tom Loney Mohamed El-Sadig Abderrahim Oulhaj Leila Abdel Wareth Wael Al Mahmeed Habiba Alsafar Benjamin Hirsch Fatme Al Anouti Jamila Yaaqoub Claire K. Inman Aisha Al Hamiz Ayesha Al Hosani Muna Haji Teeb Alsharid Thekra Al Zaabi Fatima Al Maisary Divya Galani Tim Sprosen Omar El Shahawy Jiyoung Ahn Tomas Kirchhoff Ravichandran Ramasamy Ann Marie Schmidt Richard Hayes Scott Sherman Raghib Ali The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals BMC Public Health Adult Chronic disease Cohort studies Pilot projects Prospective studies Public health |
| title | The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals |
| title_full | The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals |
| title_fullStr | The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals |
| title_full_unstemmed | The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals |
| title_short | The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals |
| title_sort | uae healthy future study a pilot for a prospective cohort study of 20 000 united arab emirates nationals |
| topic | Adult Chronic disease Cohort studies Pilot projects Prospective studies Public health |
| url | http://link.springer.com/article/10.1186/s12889-017-5012-2 |
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