Modular microfluidics for life sciences
Abstract The advancement of microfluidics has enabled numerous discoveries and technologies in life sciences. However, due to the lack of industry standards and configurability, the design and fabrication of microfluidic devices require highly skilled technicians. The diversity of microfluidic devic...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-03-01
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| Series: | Journal of Nanobiotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12951-023-01846-x |
| _version_ | 1797863647147458560 |
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| author | Jialin Wu Hui Fang Jun Zhang Sheng Yan |
| author_facet | Jialin Wu Hui Fang Jun Zhang Sheng Yan |
| author_sort | Jialin Wu |
| collection | DOAJ |
| description | Abstract The advancement of microfluidics has enabled numerous discoveries and technologies in life sciences. However, due to the lack of industry standards and configurability, the design and fabrication of microfluidic devices require highly skilled technicians. The diversity of microfluidic devices discourages biologists and chemists from applying this technique in their laboratories. Modular microfluidics, which integrates the standardized microfluidic modules into a whole, complex platform, brings the capability of configurability to conventional microfluidics. The exciting features, including portability, on-site deployability, and high customization motivate us to review the state-of-the-art modular microfluidics and discuss future perspectives. In this review, we first introduce the working mechanisms of the basic microfluidic modules and evaluate their feasibility as modular microfluidic components. Next, we explain the connection approaches among these microfluidic modules, and summarize the advantages of modular microfluidics over integrated microfluidics in biological applications. Finally, we discuss the challenge and future perspectives of modular microfluidics. |
| first_indexed | 2024-04-09T22:38:53Z |
| format | Article |
| id | doaj.art-04e367137424435cbe5b37f9ccd77b4c |
| institution | Directory Open Access Journal |
| issn | 1477-3155 |
| language | English |
| last_indexed | 2024-04-09T22:38:53Z |
| publishDate | 2023-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Nanobiotechnology |
| spelling | doaj.art-04e367137424435cbe5b37f9ccd77b4c2023-03-22T12:16:36ZengBMCJournal of Nanobiotechnology1477-31552023-03-0121113010.1186/s12951-023-01846-xModular microfluidics for life sciencesJialin Wu0Hui Fang1Jun Zhang2Sheng Yan3Institute for Advanced Study, Shenzhen UniversityNanophotonics Research Center, Institute of Microscale Optoelectronics, Shenzhen UniversityQueensland Micro and Nanotechnology Centre, Griffith UniversityInstitute for Advanced Study, Shenzhen UniversityAbstract The advancement of microfluidics has enabled numerous discoveries and technologies in life sciences. However, due to the lack of industry standards and configurability, the design and fabrication of microfluidic devices require highly skilled technicians. The diversity of microfluidic devices discourages biologists and chemists from applying this technique in their laboratories. Modular microfluidics, which integrates the standardized microfluidic modules into a whole, complex platform, brings the capability of configurability to conventional microfluidics. The exciting features, including portability, on-site deployability, and high customization motivate us to review the state-of-the-art modular microfluidics and discuss future perspectives. In this review, we first introduce the working mechanisms of the basic microfluidic modules and evaluate their feasibility as modular microfluidic components. Next, we explain the connection approaches among these microfluidic modules, and summarize the advantages of modular microfluidics over integrated microfluidics in biological applications. Finally, we discuss the challenge and future perspectives of modular microfluidics.https://doi.org/10.1186/s12951-023-01846-xBioMEMSModular microfluidicsBiotechnologyLife ScienceMicrochannel connection |
| spellingShingle | Jialin Wu Hui Fang Jun Zhang Sheng Yan Modular microfluidics for life sciences Journal of Nanobiotechnology BioMEMS Modular microfluidics Biotechnology Life Science Microchannel connection |
| title | Modular microfluidics for life sciences |
| title_full | Modular microfluidics for life sciences |
| title_fullStr | Modular microfluidics for life sciences |
| title_full_unstemmed | Modular microfluidics for life sciences |
| title_short | Modular microfluidics for life sciences |
| title_sort | modular microfluidics for life sciences |
| topic | BioMEMS Modular microfluidics Biotechnology Life Science Microchannel connection |
| url | https://doi.org/10.1186/s12951-023-01846-x |
| work_keys_str_mv | AT jialinwu modularmicrofluidicsforlifesciences AT huifang modularmicrofluidicsforlifesciences AT junzhang modularmicrofluidicsforlifesciences AT shengyan modularmicrofluidicsforlifesciences |