Lymphoma presenting as subcutaneous periorbital nodules
A 67-year-old female presented with a several month history of painless enlarging right periorbital growths. Examination showed multiple nontender subcutaneous nodules superior to the right eyebrow. Magnetic resonance imaging and incisional biopsy confirmed subcutaneous marginal zone B-cell lymphoma...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Clinical Dermatology Review |
| Subjects: | |
| Online Access: | http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2018;volume=2;issue=2;spage=81;epage=82;aulast=DeMaria |
| _version_ | 1818455737802686464 |
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| author | Lauren N DeMaria Codrin E Iacob Roman Shinder |
| author_facet | Lauren N DeMaria Codrin E Iacob Roman Shinder |
| author_sort | Lauren N DeMaria |
| collection | DOAJ |
| description | A 67-year-old female presented with a several month history of painless enlarging right periorbital growths. Examination showed multiple nontender subcutaneous nodules superior to the right eyebrow. Magnetic resonance imaging and incisional biopsy confirmed subcutaneous marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). Subcutaneous involvement sparing the epidermis is a rare presentation in patients with prior noncutaneous marginal zone lymphomas. Recent studies have demonstrated that subcutaneous dissemination is associated with MALT lymphoma of the breast and ocular adnexa. Systemic workup is therefore critical in patients who present with subcutaneous MALT lymphoma. Radiation therapy has proven to be effective in cutaneous marginal zone B-cell lymphomas. |
| first_indexed | 2024-12-14T22:15:32Z |
| format | Article |
| id | doaj.art-04e6070036974e8299d2db58ccdd3b3d |
| institution | Directory Open Access Journal |
| issn | 2542-551X 2542-5528 |
| language | English |
| last_indexed | 2024-12-14T22:15:32Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Clinical Dermatology Review |
| spelling | doaj.art-04e6070036974e8299d2db58ccdd3b3d2022-12-21T22:45:38ZengWolters Kluwer Medknow PublicationsClinical Dermatology Review2542-551X2542-55282018-01-0122818210.4103/CDR.CDR_44_17Lymphoma presenting as subcutaneous periorbital nodulesLauren N DeMariaCodrin E IacobRoman ShinderA 67-year-old female presented with a several month history of painless enlarging right periorbital growths. Examination showed multiple nontender subcutaneous nodules superior to the right eyebrow. Magnetic resonance imaging and incisional biopsy confirmed subcutaneous marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). Subcutaneous involvement sparing the epidermis is a rare presentation in patients with prior noncutaneous marginal zone lymphomas. Recent studies have demonstrated that subcutaneous dissemination is associated with MALT lymphoma of the breast and ocular adnexa. Systemic workup is therefore critical in patients who present with subcutaneous MALT lymphoma. Radiation therapy has proven to be effective in cutaneous marginal zone B-cell lymphomas.http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2018;volume=2;issue=2;spage=81;epage=82;aulast=DeMarialymphomamucosa-associated lymphoid tissuesubcutaneous |
| spellingShingle | Lauren N DeMaria Codrin E Iacob Roman Shinder Lymphoma presenting as subcutaneous periorbital nodules Clinical Dermatology Review lymphoma mucosa-associated lymphoid tissue subcutaneous |
| title | Lymphoma presenting as subcutaneous periorbital nodules |
| title_full | Lymphoma presenting as subcutaneous periorbital nodules |
| title_fullStr | Lymphoma presenting as subcutaneous periorbital nodules |
| title_full_unstemmed | Lymphoma presenting as subcutaneous periorbital nodules |
| title_short | Lymphoma presenting as subcutaneous periorbital nodules |
| title_sort | lymphoma presenting as subcutaneous periorbital nodules |
| topic | lymphoma mucosa-associated lymphoid tissue subcutaneous |
| url | http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2018;volume=2;issue=2;spage=81;epage=82;aulast=DeMaria |
| work_keys_str_mv | AT laurenndemaria lymphomapresentingassubcutaneousperiorbitalnodules AT codrineiacob lymphomapresentingassubcutaneousperiorbitalnodules AT romanshinder lymphomapresentingassubcutaneousperiorbitalnodules |