The Effect of Phototherapy with Blue Light in Treatment Acne Vulgaris in Compare with Conventional Therapy with Tetracycline
Background: Acne Vulgaris is a common inflammatory disease of pilosebaceous follicles that affect about 90 percent of the adolescents. Phototherapy has been suggested as an alternative treatment for acne. Phototherapy with blue light (wavelength 405-420 nm) is one of these methods with a good therap...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | fas |
| Published: |
Isfahan University of Medical Sciences
2011-04-01
|
| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/877 |
| _version_ | 1797716497624203264 |
|---|---|
| author | Gita Faghihi Anahita Vali Nafiseh Sarraf Bank Elnaz Ahmadieh |
| author_facet | Gita Faghihi Anahita Vali Nafiseh Sarraf Bank Elnaz Ahmadieh |
| author_sort | Gita Faghihi |
| collection | DOAJ |
| description | Background: Acne Vulgaris is a common inflammatory disease of pilosebaceous follicles that affect about 90 percent of the adolescents. Phototherapy has been suggested as an alternative treatment for acne. Phototherapy with blue light (wavelength 405-420 nm) is one of these methods with a good therapeutic effect on inflammatory acne lesions. In this study, the effect of treatment of acne by phototherapy with blue light was compared with conventional tetracycline treatments.
Methods: This was a prospective clinical trial study on patients with mild to moderate acne vulgaris. Patients were randomly devided in two groups of 44 subjects (phototherapy or standard treatment). Patients in both groups were followed every 4 weeks to 12 weeks. Type and number of lesions and acne severity index (ASI) were studied before starting the study, during treatment and at each visit. The data were analyzed by Student-t and chi-square test.
Finding: The mean age of patients in both groups did not differ significantly. The incidence of comedones, papules, pustules and the mean of acne severity index in reference group that received standard therapy were significantly less than the phototherapy group.
Conclusion: This study showed that the effect of phototherapy on comedones is less than inflammatory lesions that may occur because of antibacterial effect of phototherapy with blue light on Propionibacterium acnes. Based on the results, the neonatal phototherapy lamps is not appropriate to obtain a therapeutic effect on acne vulgaris. |
| first_indexed | 2024-03-12T08:22:18Z |
| format | Article |
| id | doaj.art-04e61e9395f742bca0b0511d89a2ce07 |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T08:22:18Z |
| publishDate | 2011-04-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-04e61e9395f742bca0b0511d89a2ce072023-09-02T18:20:31ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2011-04-012812318941900593The Effect of Phototherapy with Blue Light in Treatment Acne Vulgaris in Compare with Conventional Therapy with TetracyclineGita Faghihi0Anahita Vali1Nafiseh Sarraf Bank2Elnaz Ahmadieh3Associate Professor, Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.Assistant Professor, Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.Medical Student, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.Medical Student, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.Background: Acne Vulgaris is a common inflammatory disease of pilosebaceous follicles that affect about 90 percent of the adolescents. Phototherapy has been suggested as an alternative treatment for acne. Phototherapy with blue light (wavelength 405-420 nm) is one of these methods with a good therapeutic effect on inflammatory acne lesions. In this study, the effect of treatment of acne by phototherapy with blue light was compared with conventional tetracycline treatments. Methods: This was a prospective clinical trial study on patients with mild to moderate acne vulgaris. Patients were randomly devided in two groups of 44 subjects (phototherapy or standard treatment). Patients in both groups were followed every 4 weeks to 12 weeks. Type and number of lesions and acne severity index (ASI) were studied before starting the study, during treatment and at each visit. The data were analyzed by Student-t and chi-square test. Finding: The mean age of patients in both groups did not differ significantly. The incidence of comedones, papules, pustules and the mean of acne severity index in reference group that received standard therapy were significantly less than the phototherapy group. Conclusion: This study showed that the effect of phototherapy on comedones is less than inflammatory lesions that may occur because of antibacterial effect of phototherapy with blue light on Propionibacterium acnes. Based on the results, the neonatal phototherapy lamps is not appropriate to obtain a therapeutic effect on acne vulgaris.http://jims.mui.ac.ir/index.php/jims/article/view/877Acne vulgarisPhototherapyAcne severity index |
| spellingShingle | Gita Faghihi Anahita Vali Nafiseh Sarraf Bank Elnaz Ahmadieh The Effect of Phototherapy with Blue Light in Treatment Acne Vulgaris in Compare with Conventional Therapy with Tetracycline مجله دانشکده پزشکی اصفهان Acne vulgaris Phototherapy Acne severity index |
| title | The Effect of Phototherapy with Blue Light in Treatment Acne Vulgaris in Compare with Conventional Therapy with Tetracycline |
| title_full | The Effect of Phototherapy with Blue Light in Treatment Acne Vulgaris in Compare with Conventional Therapy with Tetracycline |
| title_fullStr | The Effect of Phototherapy with Blue Light in Treatment Acne Vulgaris in Compare with Conventional Therapy with Tetracycline |
| title_full_unstemmed | The Effect of Phototherapy with Blue Light in Treatment Acne Vulgaris in Compare with Conventional Therapy with Tetracycline |
| title_short | The Effect of Phototherapy with Blue Light in Treatment Acne Vulgaris in Compare with Conventional Therapy with Tetracycline |
| title_sort | effect of phototherapy with blue light in treatment acne vulgaris in compare with conventional therapy with tetracycline |
| topic | Acne vulgaris Phototherapy Acne severity index |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/877 |
| work_keys_str_mv | AT gitafaghihi theeffectofphototherapywithbluelightintreatmentacnevulgarisincomparewithconventionaltherapywithtetracycline AT anahitavali theeffectofphototherapywithbluelightintreatmentacnevulgarisincomparewithconventionaltherapywithtetracycline AT nafisehsarrafbank theeffectofphototherapywithbluelightintreatmentacnevulgarisincomparewithconventionaltherapywithtetracycline AT elnazahmadieh theeffectofphototherapywithbluelightintreatmentacnevulgarisincomparewithconventionaltherapywithtetracycline AT gitafaghihi effectofphototherapywithbluelightintreatmentacnevulgarisincomparewithconventionaltherapywithtetracycline AT anahitavali effectofphototherapywithbluelightintreatmentacnevulgarisincomparewithconventionaltherapywithtetracycline AT nafisehsarrafbank effectofphototherapywithbluelightintreatmentacnevulgarisincomparewithconventionaltherapywithtetracycline AT elnazahmadieh effectofphototherapywithbluelightintreatmentacnevulgarisincomparewithconventionaltherapywithtetracycline |