Background and descriptive features of rabies-suspected animals in Central Luzon, Philippines
Abstract Background The Philippines is one of the major endemic countries for canine rabies in Southeast Asia. However, detailed description and analysis of laboratory-confirmed animal rabies are limited. Highly accurate surveillance requires a thorough understanding of the target area-specific prob...
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| Format: | Article |
| Language: | English |
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BMC
2021-07-01
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| Series: | Tropical Medicine and Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41182-021-00351-x |
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| author | Milagros R. Mananggit Kazunori Kimitsuki Nobuo Saito Alyssa Marie G. Garcia Patricia Mae T. Lacanilao Joely T. Ongtangco Cornelio R. Velasco Maria Victoria D. Rosario Maria Glofezita O. Lagayan Kentaro Yamada Chun-Ho Park Satoshi Inoue Motoi Suzuki Mariko Saito-Obata Yasuhiko Kamiya Daria L. Manalo Catalino S. Demetria Beatriz P. Quiambao Akira Nishizono |
| author_facet | Milagros R. Mananggit Kazunori Kimitsuki Nobuo Saito Alyssa Marie G. Garcia Patricia Mae T. Lacanilao Joely T. Ongtangco Cornelio R. Velasco Maria Victoria D. Rosario Maria Glofezita O. Lagayan Kentaro Yamada Chun-Ho Park Satoshi Inoue Motoi Suzuki Mariko Saito-Obata Yasuhiko Kamiya Daria L. Manalo Catalino S. Demetria Beatriz P. Quiambao Akira Nishizono |
| author_sort | Milagros R. Mananggit |
| collection | DOAJ |
| description | Abstract Background The Philippines is one of the major endemic countries for canine rabies in Southeast Asia. However, detailed description and analysis of laboratory-confirmed animal rabies are limited. Highly accurate surveillance requires a thorough understanding of the target area-specific problems and obstacles. Therefore, we aim to describe and analyze the rabies suspect animals in Central Luzon, Philippines, to clarify the characteristics of management and clinical signs by conducting interviews with the owners. Methods We prospectively collected information on the rabies suspect animals submitted to the Regional animal laboratory in Central Luzon through passive laboratory-based rabies surveillance between 1st April 2019 and 30th September 2020. We performed active interviews directly or telephonically with the owner. The direct fluorescent antibody test was performed on the hippocampus, brain stem, and cerebellum for laboratory confirmation. Descriptive statistics were used to characterize the number of rabies cases according to management methods and characteristics of suspected animals during the observation period. Clinical symptoms of suspected rabid animals were analyzed by univariate logistic regression analysis. Results There were 292 sample submissions during the study period. Of these, 160 were positive for dFAT. Samples of pet animals (85.3%) provided by owners or their acquaintances (59.2%) accounted for the majority of laboratory confirmed cases. Case mapping showed that more rabies-suspected cases were sent from areas near the regional laboratory than from those far from the laboratory, despite the incidence of rabies being high in these areas. The management and clinical symptoms of 227 animal cases showed that most owners were managing their animals at home and were allowing them to roam outside (69.6%) and be unvaccinated (78.9%). Rabid animals were more likely to manifest aimless running, restlessness, and agitation. Conclusions Our study provided some features of animals with laboratory-confirmed rabies in Central Luzon. However, most of the samples were submitted from areas near the rabies diagnosis laboratory, and the number of samples submitted from remote areas was low. To improve the surveillance capacity, it is necessary to increase sample submissions from remote areas. |
| first_indexed | 2024-12-13T20:37:48Z |
| format | Article |
| id | doaj.art-04ed9b55d1ee4808ad4b2cb3dcaf7c0b |
| institution | Directory Open Access Journal |
| issn | 1349-4147 |
| language | English |
| last_indexed | 2024-12-13T20:37:48Z |
| publishDate | 2021-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Tropical Medicine and Health |
| spelling | doaj.art-04ed9b55d1ee4808ad4b2cb3dcaf7c0b2022-12-21T23:32:14ZengBMCTropical Medicine and Health1349-41472021-07-014911910.1186/s41182-021-00351-xBackground and descriptive features of rabies-suspected animals in Central Luzon, PhilippinesMilagros R. Mananggit0Kazunori Kimitsuki1Nobuo Saito2Alyssa Marie G. Garcia3Patricia Mae T. Lacanilao4Joely T. Ongtangco5Cornelio R. Velasco6Maria Victoria D. Rosario7Maria Glofezita O. Lagayan8Kentaro Yamada9Chun-Ho Park10Satoshi Inoue11Motoi Suzuki12Mariko Saito-Obata13Yasuhiko Kamiya14Daria L. Manalo15Catalino S. Demetria16Beatriz P. Quiambao17Akira Nishizono18Regional Animal Disease Diagnostic Laboratory, Department of Agriculture Field Office IIIDepartment of Microbiology, Faculty of Medicine, Oita UniversityDepartment of Microbiology, Faculty of Medicine, Oita UniversityRegional Animal Disease Diagnostic Laboratory, Department of Agriculture Field Office IIIRegional Animal Disease Diagnostic Laboratory, Department of Agriculture Field Office IIIRegional Animal Disease Diagnostic Laboratory, Department of Agriculture Field Office IIIRegional Animal Disease Diagnostic Laboratory, Department of Agriculture Field Office IIIRegional Animal Disease Diagnostic Laboratory, Department of Agriculture Field Office IIISchool of Tropical Medicine and Global Health, Nagasaki UniversityDepartment of Microbiology, Faculty of Medicine, Oita UniversityDepartment of Veterinary Pathology, School of Veterinary Medicine, Kitasato UniversityDepartment of Veterinary Pathology, School of Veterinary Medicine, Kitasato UniversitySchool of Tropical Medicine and Global Health, Nagasaki UniversityTohoku University Graduate School of MedicineSchool of Tropical Medicine and Global Health, Nagasaki UniversityResearch Institute for Tropical MedicineDepartment of Microbiology, Faculty of Medicine, Oita UniversityResearch Institute for Tropical MedicineDepartment of Microbiology, Faculty of Medicine, Oita UniversityAbstract Background The Philippines is one of the major endemic countries for canine rabies in Southeast Asia. However, detailed description and analysis of laboratory-confirmed animal rabies are limited. Highly accurate surveillance requires a thorough understanding of the target area-specific problems and obstacles. Therefore, we aim to describe and analyze the rabies suspect animals in Central Luzon, Philippines, to clarify the characteristics of management and clinical signs by conducting interviews with the owners. Methods We prospectively collected information on the rabies suspect animals submitted to the Regional animal laboratory in Central Luzon through passive laboratory-based rabies surveillance between 1st April 2019 and 30th September 2020. We performed active interviews directly or telephonically with the owner. The direct fluorescent antibody test was performed on the hippocampus, brain stem, and cerebellum for laboratory confirmation. Descriptive statistics were used to characterize the number of rabies cases according to management methods and characteristics of suspected animals during the observation period. Clinical symptoms of suspected rabid animals were analyzed by univariate logistic regression analysis. Results There were 292 sample submissions during the study period. Of these, 160 were positive for dFAT. Samples of pet animals (85.3%) provided by owners or their acquaintances (59.2%) accounted for the majority of laboratory confirmed cases. Case mapping showed that more rabies-suspected cases were sent from areas near the regional laboratory than from those far from the laboratory, despite the incidence of rabies being high in these areas. The management and clinical symptoms of 227 animal cases showed that most owners were managing their animals at home and were allowing them to roam outside (69.6%) and be unvaccinated (78.9%). Rabid animals were more likely to manifest aimless running, restlessness, and agitation. Conclusions Our study provided some features of animals with laboratory-confirmed rabies in Central Luzon. However, most of the samples were submitted from areas near the rabies diagnosis laboratory, and the number of samples submitted from remote areas was low. To improve the surveillance capacity, it is necessary to increase sample submissions from remote areas.https://doi.org/10.1186/s41182-021-00351-xNeglected tropical diseasesRabiesAnimal rabies caseSurveillancePhilippines |
| spellingShingle | Milagros R. Mananggit Kazunori Kimitsuki Nobuo Saito Alyssa Marie G. Garcia Patricia Mae T. Lacanilao Joely T. Ongtangco Cornelio R. Velasco Maria Victoria D. Rosario Maria Glofezita O. Lagayan Kentaro Yamada Chun-Ho Park Satoshi Inoue Motoi Suzuki Mariko Saito-Obata Yasuhiko Kamiya Daria L. Manalo Catalino S. Demetria Beatriz P. Quiambao Akira Nishizono Background and descriptive features of rabies-suspected animals in Central Luzon, Philippines Tropical Medicine and Health Neglected tropical diseases Rabies Animal rabies case Surveillance Philippines |
| title | Background and descriptive features of rabies-suspected animals in Central Luzon, Philippines |
| title_full | Background and descriptive features of rabies-suspected animals in Central Luzon, Philippines |
| title_fullStr | Background and descriptive features of rabies-suspected animals in Central Luzon, Philippines |
| title_full_unstemmed | Background and descriptive features of rabies-suspected animals in Central Luzon, Philippines |
| title_short | Background and descriptive features of rabies-suspected animals in Central Luzon, Philippines |
| title_sort | background and descriptive features of rabies suspected animals in central luzon philippines |
| topic | Neglected tropical diseases Rabies Animal rabies case Surveillance Philippines |
| url | https://doi.org/10.1186/s41182-021-00351-x |
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