Present and future etiological treatment of bacterial pneumonia 3. The antibacterial drugs under development

The rapid spread of antibiotic-resistant bacterial strains necessitates the development of new antibacterial agents and a review of the guidelines for etiological treatment of bacterial infections, including pneumonia. Currently, new antibacterial agents are being developed that disrupt the biosynth...

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Main Authors: A.A. Abaturov, T.A. Kryuchko
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2017-08-01
Series:Zdorovʹe Rebenka
Subjects:
Online Access:http://childshealth.zaslavsky.com.ua/article/view/109278
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author A.A. Abaturov
T.A. Kryuchko
author_facet A.A. Abaturov
T.A. Kryuchko
author_sort A.A. Abaturov
collection DOAJ
description The rapid spread of antibiotic-resistant bacterial strains necessitates the development of new antibacterial agents and a review of the guidelines for etiological treatment of bacterial infections, including pneumonia. Currently, new antibacterial agents are being developed that disrupt the biosynthesis of peptidoglycan, teichoic and lipoteichoic acids, and also block the attachment of virulent factors to the bacterial wall. New molecules of old classes of antibiotics and representatives of new classes of antibiotics with their targets (lipid II and III, teichoic and lipoteichoic acids, alanine racemase, and sortase A) will become practical tools in clinical practice in the very near future. The goals and mechanisms of action of new antibacterial compounds predetermine their clinical prospects in future strategies for the treatment of infectious bacterial diseases.
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spelling doaj.art-04efe8f1d03a44b99328abd5d71bc1cc2022-12-21T19:23:42ZengZaslavsky O.Yu.Zdorovʹe Rebenka2224-05512307-11682017-08-0112559060310.22141/2224-0551.12.5.2017.109278109278Present and future etiological treatment of bacterial pneumonia 3. The antibacterial drugs under developmentA.A. Abaturov0T.A. Kryuchko1SI “Dnipropetrovsk Medical Academy of Ministry of Health of Ukraine”, Dnipro, UkraineHSEIU “Ukrainian Medical Stomatological Academy”, Poltava, UkraineThe rapid spread of antibiotic-resistant bacterial strains necessitates the development of new antibacterial agents and a review of the guidelines for etiological treatment of bacterial infections, including pneumonia. Currently, new antibacterial agents are being developed that disrupt the biosynthesis of peptidoglycan, teichoic and lipoteichoic acids, and also block the attachment of virulent factors to the bacterial wall. New molecules of old classes of antibiotics and representatives of new classes of antibiotics with their targets (lipid II and III, teichoic and lipoteichoic acids, alanine racemase, and sortase A) will become practical tools in clinical practice in the very near future. The goals and mechanisms of action of new antibacterial compounds predetermine their clinical prospects in future strategies for the treatment of infectious bacterial diseases.http://childshealth.zaslavsky.com.ua/article/view/109278bacterial pneumoniachildrenantibacterial drugs
spellingShingle A.A. Abaturov
T.A. Kryuchko
Present and future etiological treatment of bacterial pneumonia 3. The antibacterial drugs under development
Zdorovʹe Rebenka
bacterial pneumonia
children
antibacterial drugs
title Present and future etiological treatment of bacterial pneumonia 3. The antibacterial drugs under development
title_full Present and future etiological treatment of bacterial pneumonia 3. The antibacterial drugs under development
title_fullStr Present and future etiological treatment of bacterial pneumonia 3. The antibacterial drugs under development
title_full_unstemmed Present and future etiological treatment of bacterial pneumonia 3. The antibacterial drugs under development
title_short Present and future etiological treatment of bacterial pneumonia 3. The antibacterial drugs under development
title_sort present and future etiological treatment of bacterial pneumonia 3 the antibacterial drugs under development
topic bacterial pneumonia
children
antibacterial drugs
url http://childshealth.zaslavsky.com.ua/article/view/109278
work_keys_str_mv AT aaabaturov presentandfutureetiologicaltreatmentofbacterialpneumonia3theantibacterialdrugsunderdevelopment
AT takryuchko presentandfutureetiologicaltreatmentofbacterialpneumonia3theantibacterialdrugsunderdevelopment