Nucleophile sensitivity of Drosophila TRPA1 underlies light-induced feeding deterrence

Nucleophile sensitivity of Drosophila TRPA1 underlies light-induced feeding deterrence

Solar irradiation including ultraviolet (UV) light causes tissue damage by generating reactive free radicals that can be electrophilic or nucleophilic due to unpaired electrons. Little is known about how free radicals induced by natural sunlight are rapidly detected and avoided by animals. We discov...

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Bibliographic Details
Main Authors: Eun Jo Du, Tae Jung Ahn, Xianlan Wen, Dae-Won Seo, Duk L Na, Jae Young Kwon, Myunghwan Choi, Hyung-Wook Kim, Hana Cho, KyeongJin Kang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
chemical nociception
photochemistry
free radicals
nucleophiles
TRPA1
feeding deterrence
Online Access:https://elifesciences.org/articles/18425

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