Synthesis, Cytotoxic Activity, Crystal Structure, DFT, Molecular Docking Study of <i>β</i>-Enaminonitrile Incorporating 1<i>H</i>-Benzo[<i>f</i>]Chromene Moiety

Synthesis, Cytotoxic Activity, Crystal Structure, DFT, Molecular Docking Study of <i>β</i>-Enaminonitrile Incorporating 1<i>H</i>-Benzo[<i>f</i>]Chromene Moiety

In this work, we used microwave irradiation conditions to synthesize <i>β</i>-enaminonitrile (<b>4</b>), which was affirmed using single crystal X-ray diffraction and the different spectral data. Two tumor cell lines, MCF-7 and MCF-7/ADR, as well as two normal cell lines, HFL...

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Bibliographic Details
Main Authors:	Mosa H. Alsehli, Lali M. Al-Harbi, Rawda M. Okasha, Ahmed M. Fouda, Hazem A. Ghabbour, Abd El-Galil E. Amr, Ahmed A. Elhenawy, Ahmed M. El-Agrody
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	Crystals
Subjects:	β-enaminonitrile microwave irradiation X-ray antitumor activity docking study
Online Access:	https://www.mdpi.com/2073-4352/13/1/24

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