Activation of RHO-1 in cholinergic motor neurons competes with dopamine signalling to control locomotion.

Activation of RHO-1 in cholinergic motor neurons competes with dopamine signalling to control locomotion.

The small GTPase RhoA plays a crucial role in the regulation of neuronal signalling to generate behaviour. In the developing nervous system RhoA is known to regulate the actin cytoskeleton, however the effectors of RhoA-signalling in adult neurons remain largely unidentified. We have previously show...

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Bibliographic Details
Main Authors: Clara L Essmann, Katie R Ryan, Muna Elmi, Kimberley Bryon-Dodd, Andrew Porter, Andrew Vaughan, Rachel McMullan, Stephen Nurrish
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6150489?pdf=render

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