Donor lung derived myeloid and plasmacytoid dendritic cells differentially regulate T cell proliferation and cytokine production

Donor lung derived myeloid and plasmacytoid dendritic cells differentially regulate T cell proliferation and cytokine production

<p>Abstract</p> <p>Background</p> <p>Direct allorecognition, i.e., donor lung-derived dendritic cells (DCs) stimulating recipient-derived T lymphocytes, is believed to be the key mechanism of lung allograft rejection. Myeloid (cDCs) and plasmacytoid (pDCs) are believed...

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Bibliographic Details
Main Authors: Benson Heather L, Suzuki Hidemi, Lott Jeremy, Fisher Amanda, Walline Crystal, Heidler Kathleen M, Brutkiewicz Randy, Blum Janice S, Wilkes David S
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Respiratory Research
Subjects:
Lung transplantation
dendritic cells
mouse
T cell activation
Online Access:http://respiratory-research.com/content/13/1/25

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