Endothelial angiopoietin-2 overexpression in explanted livers identifies subjects at higher risk of recurrence of hepatocellular carcinoma after liver transplantation

Endothelial angiopoietin-2 overexpression in explanted livers identifies subjects at higher risk of recurrence of hepatocellular carcinoma after liver transplantation

BackgroundThough the precise criteria for accessing LT are consistently being applied, HCC recurrence (HCC-R_LT) still affects more than 15% of the patients. We analyzed the clinical, histopathological, and biological features of patients with HCC to identify the predictive factors associated with c...

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Main Authors: Simone Lasagni, Filippo Leonardi, Alessandra Pivetti, Lorenza Di Marco, Federico Ravaioli, Matteo Serenari, Stefano Gitto, Rosina Maria Critelli, Fabiola Milosa, Adriana Romanzi, Serena Mancarella, Francesco Dituri, Mattia Riefolo, Barbara Catellani, Paolo Magistri, Dante Romagnoli, Ciro Celsa, Marco Enea, Nicola de Maria, Filippo Schepis, Antonio Colecchia, Calogero Cammà, Matteo Cescon, Antonietta d’Errico, Fabrizio di Benedetto, Gianluigi Giannelli, Maria Luz Martinez-Chantar, Erica Villa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
liver transplantation
recurrence
angiopoietin-2
survival
neoangiogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.960808/full

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