Latent opportunities for the prevention of ischemic stroke in patients with atherosclerosis-related diseases: additional analysis of randomized trials on rivaroxaban
Practical introduction of drugs requires determining the relationship between the benefits of its use and adverse effects, as well as identifying clinically significant additional benefits of new treatment approaches by analyzing additional parameters or reanalyzing data of randomized controlled tri...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2020-03-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/3747 |
| _version_ | 1797856725031714816 |
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| author | S. R. Gilyarevskiy |
| author_facet | S. R. Gilyarevskiy |
| author_sort | S. R. Gilyarevskiy |
| collection | DOAJ |
| description | Practical introduction of drugs requires determining the relationship between the benefits of its use and adverse effects, as well as identifying clinically significant additional benefits of new treatment approaches by analyzing additional parameters or reanalyzing data of randomized controlled trials. Despite the lack of evidence of such analyzes, they often affect the prospects of using drugs in a particular clinical situation. The article discusses new data on the prospects for the use of low-dose rivaroxaban (2,5 mg 2 times a day), which were obtained not only in initial analyzes, but also secondary analyzes of data obtained in randomized trials involving patients with atherosclerosis-related cardiovascular diseases and sinus rhythm. |
| first_indexed | 2024-04-09T20:45:11Z |
| format | Article |
| id | doaj.art-0501dd80f81c4ac3a5fb4dc398b96500 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:45:11Z |
| publishDate | 2020-03-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-0501dd80f81c4ac3a5fb4dc398b965002023-03-29T21:23:34Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202020-03-0125210.15829/1560-4071-2020-2-37472860Latent opportunities for the prevention of ischemic stroke in patients with atherosclerosis-related diseases: additional analysis of randomized trials on rivaroxabanS. R. Gilyarevskiy0Russian Medical Academy of Continuing Professional EducationPractical introduction of drugs requires determining the relationship between the benefits of its use and adverse effects, as well as identifying clinically significant additional benefits of new treatment approaches by analyzing additional parameters or reanalyzing data of randomized controlled trials. Despite the lack of evidence of such analyzes, they often affect the prospects of using drugs in a particular clinical situation. The article discusses new data on the prospects for the use of low-dose rivaroxaban (2,5 mg 2 times a day), which were obtained not only in initial analyzes, but also secondary analyzes of data obtained in randomized trials involving patients with atherosclerosis-related cardiovascular diseases and sinus rhythm.https://russjcardiol.elpub.ru/jour/article/view/3747ischemic strokerivaroxabanlow doses |
| spellingShingle | S. R. Gilyarevskiy Latent opportunities for the prevention of ischemic stroke in patients with atherosclerosis-related diseases: additional analysis of randomized trials on rivaroxaban Российский кардиологический журнал ischemic stroke rivaroxaban low doses |
| title | Latent opportunities for the prevention of ischemic stroke in patients with atherosclerosis-related diseases: additional analysis of randomized trials on rivaroxaban |
| title_full | Latent opportunities for the prevention of ischemic stroke in patients with atherosclerosis-related diseases: additional analysis of randomized trials on rivaroxaban |
| title_fullStr | Latent opportunities for the prevention of ischemic stroke in patients with atherosclerosis-related diseases: additional analysis of randomized trials on rivaroxaban |
| title_full_unstemmed | Latent opportunities for the prevention of ischemic stroke in patients with atherosclerosis-related diseases: additional analysis of randomized trials on rivaroxaban |
| title_short | Latent opportunities for the prevention of ischemic stroke in patients with atherosclerosis-related diseases: additional analysis of randomized trials on rivaroxaban |
| title_sort | latent opportunities for the prevention of ischemic stroke in patients with atherosclerosis related diseases additional analysis of randomized trials on rivaroxaban |
| topic | ischemic stroke rivaroxaban low doses |
| url | https://russjcardiol.elpub.ru/jour/article/view/3747 |
| work_keys_str_mv | AT srgilyarevskiy latentopportunitiesforthepreventionofischemicstrokeinpatientswithatherosclerosisrelateddiseasesadditionalanalysisofrandomizedtrialsonrivaroxaban |