THE EFFECT OF INSULIN AND CARBOHYDRATE SUPPLEMENTATION ON GLYCOGEN REPLENISHMENT AMONG DIFFERENT HINDLIMB MUSCLES IN RATS FOLLOWING PROLONGED SWIMMING
In the present study we investigated the interactive effects of insulin and carbohydrate on glycogen replenishment in different rat hindlimb muscles. Forty male Sprague Dawley rats were assigned to 5 groups, including 1) sedentary control with carbohydrate supplement (2 g glucose · kg body wt-1), 2)...
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| Format: | Article |
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Termedia Publishing House
2012-04-01
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| Series: | Biology of Sport |
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| Online Access: | https://www.termedia.pl/Original-paper-THE-EFFECT-OF-INSULIN-AND-CARBOHYDRATE-SUPPLEMENTATION-ON-GLYCOGEN-REPLENISHMENT-AMONG-DIFFERENT-HINDLIMB-MUSCLES-IN-RATS-FOLLOWING-PROLONGED-SWIMMING,78,23386,0,1.html |
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| author | Mei-Chich Hsu Chung-Yu Chen Ching-Hung Lin Yi-Hung Liao Chia-Hua Kuo Chien-Wen Hou |
| author_facet | Mei-Chich Hsu Chung-Yu Chen Ching-Hung Lin Yi-Hung Liao Chia-Hua Kuo Chien-Wen Hou |
| author_sort | Mei-Chich Hsu |
| collection | DOAJ |
| description | In the present study we investigated the interactive effects of insulin and carbohydrate on glycogen replenishment in different rat hindlimb muscles. Forty male Sprague Dawley rats were assigned to 5 groups, including 1) sedentary control with carbohydrate supplement (2 g glucose · kg body wt-1), 2) sedentary rats with 16 hours recovery, carbohydrate and insulin (0.5 U · kg body wt-1), 3) swimming without recovery, 4) swimming with 16 hours recovery and carbohydrate supplement, and 5) swimming with 16 hours recovery, carbohydrate and insulin. The swimming protocol consisted of two 3 h swimming sections, which were separated by a 45 min rest. The insulin and carbohydrate were administered to the rats immediately after exercise. At the end of the experiment, the soleus (S), plantaris (P), quadriceps (Q) and gastrocnemius (G) were surgically excised to evaluate glycogen utilization and replenishment. We observed that glycogen utilization was significantly lower in G and Q than S and P during swimming (p <0.05), and S showed the greatest capacity of glycogen resynthesis after post-exercise recovery (p <0.05). In the sedentary state, the glycogen synthesis did not differ among hindlimb muscles during insulin and carbohydrate treatments. Interestingly, with insulin and carbohydrate, the glycogen resynthesis in S and P were significantly greater than in Q and G following post-exercise recovery (p <0.05). We therefore concluded that the soleus and plantaris are the primary working muscles during swimming, and the greatest glycogen replenishment capacity of the soleus during post-exercise recovery is likely due to its highest insulin sensitivity. |
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| issn | 0860-021X 2083-1862 |
| language | English |
| last_indexed | 2024-03-12T00:13:39Z |
| publishDate | 2012-04-01 |
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| series | Biology of Sport |
| spelling | doaj.art-0507a59eb6644a03a1f6a7f0862281cd2023-09-15T16:34:52ZengTermedia Publishing HouseBiology of Sport0860-021X2083-18622012-04-01292145150THE EFFECT OF INSULIN AND CARBOHYDRATE SUPPLEMENTATION ON GLYCOGEN REPLENISHMENT AMONG DIFFERENT HINDLIMB MUSCLES IN RATS FOLLOWING PROLONGED SWIMMINGMei-Chich HsuChung-Yu ChenChing-Hung LinYi-Hung LiaoChia-Hua KuoChien-Wen HouIn the present study we investigated the interactive effects of insulin and carbohydrate on glycogen replenishment in different rat hindlimb muscles. Forty male Sprague Dawley rats were assigned to 5 groups, including 1) sedentary control with carbohydrate supplement (2 g glucose · kg body wt-1), 2) sedentary rats with 16 hours recovery, carbohydrate and insulin (0.5 U · kg body wt-1), 3) swimming without recovery, 4) swimming with 16 hours recovery and carbohydrate supplement, and 5) swimming with 16 hours recovery, carbohydrate and insulin. The swimming protocol consisted of two 3 h swimming sections, which were separated by a 45 min rest. The insulin and carbohydrate were administered to the rats immediately after exercise. At the end of the experiment, the soleus (S), plantaris (P), quadriceps (Q) and gastrocnemius (G) were surgically excised to evaluate glycogen utilization and replenishment. We observed that glycogen utilization was significantly lower in G and Q than S and P during swimming (p <0.05), and S showed the greatest capacity of glycogen resynthesis after post-exercise recovery (p <0.05). In the sedentary state, the glycogen synthesis did not differ among hindlimb muscles during insulin and carbohydrate treatments. Interestingly, with insulin and carbohydrate, the glycogen resynthesis in S and P were significantly greater than in Q and G following post-exercise recovery (p <0.05). We therefore concluded that the soleus and plantaris are the primary working muscles during swimming, and the greatest glycogen replenishment capacity of the soleus during post-exercise recovery is likely due to its highest insulin sensitivity.https://www.termedia.pl/Original-paper-THE-EFFECT-OF-INSULIN-AND-CARBOHYDRATE-SUPPLEMENTATION-ON-GLYCOGEN-REPLENISHMENT-AMONG-DIFFERENT-HINDLIMB-MUSCLES-IN-RATS-FOLLOWING-PROLONGED-SWIMMING,78,23386,0,1.htmlswimming exercisesoleusplantarisrecovery |
| spellingShingle | Mei-Chich Hsu Chung-Yu Chen Ching-Hung Lin Yi-Hung Liao Chia-Hua Kuo Chien-Wen Hou THE EFFECT OF INSULIN AND CARBOHYDRATE SUPPLEMENTATION ON GLYCOGEN REPLENISHMENT AMONG DIFFERENT HINDLIMB MUSCLES IN RATS FOLLOWING PROLONGED SWIMMING Biology of Sport swimming exercise soleus plantaris recovery |
| title | THE EFFECT OF INSULIN AND CARBOHYDRATE SUPPLEMENTATION ON GLYCOGEN REPLENISHMENT AMONG DIFFERENT HINDLIMB MUSCLES IN RATS FOLLOWING PROLONGED SWIMMING |
| title_full | THE EFFECT OF INSULIN AND CARBOHYDRATE SUPPLEMENTATION ON GLYCOGEN REPLENISHMENT AMONG DIFFERENT HINDLIMB MUSCLES IN RATS FOLLOWING PROLONGED SWIMMING |
| title_fullStr | THE EFFECT OF INSULIN AND CARBOHYDRATE SUPPLEMENTATION ON GLYCOGEN REPLENISHMENT AMONG DIFFERENT HINDLIMB MUSCLES IN RATS FOLLOWING PROLONGED SWIMMING |
| title_full_unstemmed | THE EFFECT OF INSULIN AND CARBOHYDRATE SUPPLEMENTATION ON GLYCOGEN REPLENISHMENT AMONG DIFFERENT HINDLIMB MUSCLES IN RATS FOLLOWING PROLONGED SWIMMING |
| title_short | THE EFFECT OF INSULIN AND CARBOHYDRATE SUPPLEMENTATION ON GLYCOGEN REPLENISHMENT AMONG DIFFERENT HINDLIMB MUSCLES IN RATS FOLLOWING PROLONGED SWIMMING |
| title_sort | effect of insulin and carbohydrate supplementation on glycogen replenishment among different hindlimb muscles in rats following prolonged swimming |
| topic | swimming exercise soleus plantaris recovery |
| url | https://www.termedia.pl/Original-paper-THE-EFFECT-OF-INSULIN-AND-CARBOHYDRATE-SUPPLEMENTATION-ON-GLYCOGEN-REPLENISHMENT-AMONG-DIFFERENT-HINDLIMB-MUSCLES-IN-RATS-FOLLOWING-PROLONGED-SWIMMING,78,23386,0,1.html |
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