A single dose of exenatide had no effect on blood flow velocity in the middle cerebral artery in elderly healthy volunteers: Randomized, placebo-controlled, double-blind clinical trial

A single dose of exenatide had no effect on blood flow velocity in the middle cerebral artery in elderly healthy volunteers: Randomized, placebo-controlled, double-blind clinical trial

Background and aimsGlucagon-like peptide 1 (GLP-1) receptor agonists (GLP-1RA) are widely used for the treatment of type 2 diabetes, and recent studies indicate that they may be cardio- and neuroprotective. The safety and effect of a single dose of exenatide, a short-acting GLP-1RA, on cerebral and...

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Bibliographic Details
Main Authors: Joakim Ölmestig, Ida R. Marlet, Tina Vilsbøll, Jørgen Rungby, Egill Rostrup, Kate L. Lambertsen, Christina Kruuse
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
cerebral blood flow
healthy volunteers
glucagon-like peptide 1
exenatide
clinical trial
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.899389/full

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