Hepatocyte-like cells derived from human induced pluripotent stem cells using small molecules: implications of a transcriptomic study

Hepatocyte-like cells derived from human induced pluripotent stem cells using small molecules: implications of a transcriptomic study

Abstract Background Hepatocyte-like cells (HLCs) derived from human induced pluripotent stem cells (iPSCs) hold great promise in toxicological applications as well as in regenerative medicine. Previous efforts on hepatocyte differentiation have mostly relied on the use of growth factors (GFs) to rec...

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Bibliographic Details
Main Authors: Xiugong Gao, Rong Li, Patrick Cahan, Yang Zhao, Jeffrey J. Yourick, Robert L. Sprando
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Stem Cell Research & Therapy
Subjects:
Hepatocyte differentiation
Hepatocyte-like cells
Induced pluripotent stem cells
Transcriptomics
Small molecules
Microarray
Online Access:http://link.springer.com/article/10.1186/s13287-020-01914-1

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