Pre-pregnancy body mass index has greater influence on newborn weight and perinatal outcome than weight control during pregnancy in obese women
Abstract Background The pre-pregnancy weight and gestational weight gain (GWG) are closely related to perinatal maternal and infant complications, but the relationship between pre-pregnancy weight and GWG and the pattern of interaction have not been reported. This study investigated the influence of...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-01-01
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| Series: | Archives of Public Health |
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| Online Access: | https://doi.org/10.1186/s13690-023-01025-2 |
| _version_ | 1797952598352855040 |
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| author | Jin Zhang Rui Zhang Jingjing Chi Ya Li Wenpei Bai |
| author_facet | Jin Zhang Rui Zhang Jingjing Chi Ya Li Wenpei Bai |
| author_sort | Jin Zhang |
| collection | DOAJ |
| description | Abstract Background The pre-pregnancy weight and gestational weight gain (GWG) are closely related to perinatal maternal and infant complications, but the relationship between pre-pregnancy weight and GWG and the pattern of interaction have not been reported. This study investigated the influence of weight control during pregnancy on the perinatal maternal and infant outcomes. Methods A total of 835 singleton pregnant women who were hospitalized between January 2018 and December 2018 were retrospectively included in this study and divided into two groups: the diet guidance (DG) group (n = 167) and the control group (n = 668). The pre-pregnancy body mass index (BMI), GWG, and perinatal outcomes of the women and infants were determined in two groups. Results The dietary modification and reasonable exercise during pregnancy effectively reduced the GWG, and even some women with pre-pregnancy obesity achieved weight loss during pregnancy. The GWG in the DG group was significantly lower than in the control group, especially in the second and third trimesters. GWG was positively related to birth weight. The birth weight in the DG group was significantly lower than in the control group when their mothers had similar GWG. In women with pre-pregnancy obesity, GWG seemed to be negatively related to birth weight. However, after adjusting the mean BMI, the pre-pregnancy BMI and GWG were positively related to the birth weight. Compared with the control group, the incidences of dystocia, postpartum hemorrhage, macrosomia, small for gestational age infants and neonatal complications significantly reduced in the DG group, and the preterm birth rate was comparable between two groups. Some women with pre-pregnancy obesity lose weight during pregnancy, but there was no premature birth or small for gestational age infant. The incidences of macrosomia, postpartum hemorrhage, dystocia, cesarean section and gestational diabetes increased significantly with the increase of pre-pregnancy BMI. Conclusion For women with increased pre-pregnancy BMI, strict weight control is required to reduce obesity-related complications of the mother and infant. The weight control in the second and third trimesters is especially important and most likely to prevent GWG. Compared with GWG, pre-pregnancy BMI has greater influence on the birth weight and maternal and infant complications, and may even compromise the benefits of weight control during pregnancy. Thus, weight control is recommended before pregnancy. |
| first_indexed | 2024-04-10T22:50:00Z |
| format | Article |
| id | doaj.art-050a7f75c6824433bc04bb982a60c397 |
| institution | Directory Open Access Journal |
| issn | 2049-3258 |
| language | English |
| last_indexed | 2024-04-10T22:50:00Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Archives of Public Health |
| spelling | doaj.art-050a7f75c6824433bc04bb982a60c3972023-01-15T12:05:04ZengBMCArchives of Public Health2049-32582023-01-0181111110.1186/s13690-023-01025-2Pre-pregnancy body mass index has greater influence on newborn weight and perinatal outcome than weight control during pregnancy in obese womenJin Zhang0Rui Zhang1Jingjing Chi2Ya Li3Wenpei Bai4Department of Obstetrics and Gynaecology, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Obstetrics and Gynaecology, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Obstetrics and Gynaecology, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Obstetrics and Gynaecology, Beijing Shijitan Hospital, Capital Medical UniversityDepartment of Obstetrics and Gynaecology, Beijing Shijitan Hospital, Capital Medical UniversityAbstract Background The pre-pregnancy weight and gestational weight gain (GWG) are closely related to perinatal maternal and infant complications, but the relationship between pre-pregnancy weight and GWG and the pattern of interaction have not been reported. This study investigated the influence of weight control during pregnancy on the perinatal maternal and infant outcomes. Methods A total of 835 singleton pregnant women who were hospitalized between January 2018 and December 2018 were retrospectively included in this study and divided into two groups: the diet guidance (DG) group (n = 167) and the control group (n = 668). The pre-pregnancy body mass index (BMI), GWG, and perinatal outcomes of the women and infants were determined in two groups. Results The dietary modification and reasonable exercise during pregnancy effectively reduced the GWG, and even some women with pre-pregnancy obesity achieved weight loss during pregnancy. The GWG in the DG group was significantly lower than in the control group, especially in the second and third trimesters. GWG was positively related to birth weight. The birth weight in the DG group was significantly lower than in the control group when their mothers had similar GWG. In women with pre-pregnancy obesity, GWG seemed to be negatively related to birth weight. However, after adjusting the mean BMI, the pre-pregnancy BMI and GWG were positively related to the birth weight. Compared with the control group, the incidences of dystocia, postpartum hemorrhage, macrosomia, small for gestational age infants and neonatal complications significantly reduced in the DG group, and the preterm birth rate was comparable between two groups. Some women with pre-pregnancy obesity lose weight during pregnancy, but there was no premature birth or small for gestational age infant. The incidences of macrosomia, postpartum hemorrhage, dystocia, cesarean section and gestational diabetes increased significantly with the increase of pre-pregnancy BMI. Conclusion For women with increased pre-pregnancy BMI, strict weight control is required to reduce obesity-related complications of the mother and infant. The weight control in the second and third trimesters is especially important and most likely to prevent GWG. Compared with GWG, pre-pregnancy BMI has greater influence on the birth weight and maternal and infant complications, and may even compromise the benefits of weight control during pregnancy. Thus, weight control is recommended before pregnancy.https://doi.org/10.1186/s13690-023-01025-2Body mass index (BMI)Gestational weight gain (GWG)Birth weightObesityPregnancy |
| spellingShingle | Jin Zhang Rui Zhang Jingjing Chi Ya Li Wenpei Bai Pre-pregnancy body mass index has greater influence on newborn weight and perinatal outcome than weight control during pregnancy in obese women Archives of Public Health Body mass index (BMI) Gestational weight gain (GWG) Birth weight Obesity Pregnancy |
| title | Pre-pregnancy body mass index has greater influence on newborn weight and perinatal outcome than weight control during pregnancy in obese women |
| title_full | Pre-pregnancy body mass index has greater influence on newborn weight and perinatal outcome than weight control during pregnancy in obese women |
| title_fullStr | Pre-pregnancy body mass index has greater influence on newborn weight and perinatal outcome than weight control during pregnancy in obese women |
| title_full_unstemmed | Pre-pregnancy body mass index has greater influence on newborn weight and perinatal outcome than weight control during pregnancy in obese women |
| title_short | Pre-pregnancy body mass index has greater influence on newborn weight and perinatal outcome than weight control during pregnancy in obese women |
| title_sort | pre pregnancy body mass index has greater influence on newborn weight and perinatal outcome than weight control during pregnancy in obese women |
| topic | Body mass index (BMI) Gestational weight gain (GWG) Birth weight Obesity Pregnancy |
| url | https://doi.org/10.1186/s13690-023-01025-2 |
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