Predictive value of ‘Smartscopy’ for the detection of preinvasive cervical lesions during the COVID-19 pandemic: a diagnostic study
Objective To evaluate the performance of “Smartscopy” in diagnosing preinvasive cervical lesions among patients with abnormal cervical cancer screening results obtained during the coronavirus disease 2019 (COVID-19) pandemic. Methods This diagnostic study enrolled non-pregnant women with abnormal ce...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Obstetrics and Gynecology
2022-09-01
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| Series: | Obstetrics & Gynecology Science |
| Subjects: | |
| Online Access: | http://ogscience.org/upload/pdf/ogs-22092.pdf |
| _version_ | 1811267169873297408 |
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| author | Thamawoot Phoblap Amornrat Temtanakitpaisan Apiwat Aue-angkul Pilaiwan Kleebkaow Bandit Chumworathayi Sanguanchoke Luanratanakorn Yuwadee Itarat |
| author_facet | Thamawoot Phoblap Amornrat Temtanakitpaisan Apiwat Aue-angkul Pilaiwan Kleebkaow Bandit Chumworathayi Sanguanchoke Luanratanakorn Yuwadee Itarat |
| author_sort | Thamawoot Phoblap |
| collection | DOAJ |
| description | Objective To evaluate the performance of “Smartscopy” in diagnosing preinvasive cervical lesions among patients with abnormal cervical cancer screening results obtained during the coronavirus disease 2019 (COVID-19) pandemic. Methods This diagnostic study enrolled non-pregnant women with abnormal cervical cancer screening results obtained at the colposcopy clinic at Srinagarind Hospital (Khon Kaen, Thailand) between September 2020 and March 2021. Two colposcopists independently evaluated the uterine cervix using a smartphone and colposcopy. Cervical biopsies and endocervical curettage were performed in accordance with standard procedures. The diagnostic performance of a smartphone in detecting low-grade squamous intraepithelial lesions or worse plus (LSIL+) and high-grade squamous intraepithelial lesions plus (HSIL+) was assessed. Results In total, 247 patients were included. There was high agreement between the two colposcopists (κ=0.88; 95% confidence interval [CI], 0.82–0.93). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the smartphone to detect LSIL+ were 96.6% (95% CI, 91.6–99.1), 12.9% (95% CI, 8.06–19.2), 46.2% (95% CI, 39.7–52.4), 83.3% (95% CI, 62.6–95.3), and 0.49% (95% CI, 0.43–0.55), respectively. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of smartscopy in diagnosing HSIL+ were 67.6% (95% CI, 55.2–78.5), 85.4% (95% CI, 79.9–90.0), 60.5% (95% CI, 48.6–71.6), 88.9% (95% CI, 83.7–92.9), and 81.0% (95% CI, 0.75–0.85), respectively. Conclusion Smartscopy demonstrated a remarkable correlation with colposcopy and a high diagnostic performance value for the detection of preinvasive cervical lesions. Therefore, smartscopy may be an alternative tool for detecting abnormal cervical lesions in low to medium medical resource settings. Smartscopy may be applied in telemedicine during the COVID-19 pandemic. |
| first_indexed | 2024-04-12T20:56:33Z |
| format | Article |
| id | doaj.art-05106250525f4832a61db70990900cd7 |
| institution | Directory Open Access Journal |
| issn | 2287-8572 2287-8580 |
| language | English |
| last_indexed | 2024-04-12T20:56:33Z |
| publishDate | 2022-09-01 |
| publisher | Korean Society of Obstetrics and Gynecology |
| record_format | Article |
| series | Obstetrics & Gynecology Science |
| spelling | doaj.art-05106250525f4832a61db70990900cd72022-12-22T03:16:57ZengKorean Society of Obstetrics and GynecologyObstetrics & Gynecology Science2287-85722287-85802022-09-0165545145810.5468/ogs.220928710Predictive value of ‘Smartscopy’ for the detection of preinvasive cervical lesions during the COVID-19 pandemic: a diagnostic studyThamawoot Phoblap0Amornrat Temtanakitpaisan1Apiwat Aue-angkul2Pilaiwan Kleebkaow3Bandit Chumworathayi4Sanguanchoke Luanratanakorn5Yuwadee Itarat6Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandDepartment of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandDepartment of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandDepartment of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandDepartment of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandDepartment of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandDepartment of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandObjective To evaluate the performance of “Smartscopy” in diagnosing preinvasive cervical lesions among patients with abnormal cervical cancer screening results obtained during the coronavirus disease 2019 (COVID-19) pandemic. Methods This diagnostic study enrolled non-pregnant women with abnormal cervical cancer screening results obtained at the colposcopy clinic at Srinagarind Hospital (Khon Kaen, Thailand) between September 2020 and March 2021. Two colposcopists independently evaluated the uterine cervix using a smartphone and colposcopy. Cervical biopsies and endocervical curettage were performed in accordance with standard procedures. The diagnostic performance of a smartphone in detecting low-grade squamous intraepithelial lesions or worse plus (LSIL+) and high-grade squamous intraepithelial lesions plus (HSIL+) was assessed. Results In total, 247 patients were included. There was high agreement between the two colposcopists (κ=0.88; 95% confidence interval [CI], 0.82–0.93). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the smartphone to detect LSIL+ were 96.6% (95% CI, 91.6–99.1), 12.9% (95% CI, 8.06–19.2), 46.2% (95% CI, 39.7–52.4), 83.3% (95% CI, 62.6–95.3), and 0.49% (95% CI, 0.43–0.55), respectively. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of smartscopy in diagnosing HSIL+ were 67.6% (95% CI, 55.2–78.5), 85.4% (95% CI, 79.9–90.0), 60.5% (95% CI, 48.6–71.6), 88.9% (95% CI, 83.7–92.9), and 81.0% (95% CI, 0.75–0.85), respectively. Conclusion Smartscopy demonstrated a remarkable correlation with colposcopy and a high diagnostic performance value for the detection of preinvasive cervical lesions. Therefore, smartscopy may be an alternative tool for detecting abnormal cervical lesions in low to medium medical resource settings. Smartscopy may be applied in telemedicine during the COVID-19 pandemic.http://ogscience.org/upload/pdf/ogs-22092.pdfcervical cancer screeningcervical intraepithelial neoplasiacolposcopysmartscopycovid-19 |
| spellingShingle | Thamawoot Phoblap Amornrat Temtanakitpaisan Apiwat Aue-angkul Pilaiwan Kleebkaow Bandit Chumworathayi Sanguanchoke Luanratanakorn Yuwadee Itarat Predictive value of ‘Smartscopy’ for the detection of preinvasive cervical lesions during the COVID-19 pandemic: a diagnostic study Obstetrics & Gynecology Science cervical cancer screening cervical intraepithelial neoplasia colposcopy smartscopy covid-19 |
| title | Predictive value of ‘Smartscopy’ for the detection of preinvasive cervical lesions during the COVID-19 pandemic: a diagnostic study |
| title_full | Predictive value of ‘Smartscopy’ for the detection of preinvasive cervical lesions during the COVID-19 pandemic: a diagnostic study |
| title_fullStr | Predictive value of ‘Smartscopy’ for the detection of preinvasive cervical lesions during the COVID-19 pandemic: a diagnostic study |
| title_full_unstemmed | Predictive value of ‘Smartscopy’ for the detection of preinvasive cervical lesions during the COVID-19 pandemic: a diagnostic study |
| title_short | Predictive value of ‘Smartscopy’ for the detection of preinvasive cervical lesions during the COVID-19 pandemic: a diagnostic study |
| title_sort | predictive value of smartscopy for the detection of preinvasive cervical lesions during the covid 19 pandemic a diagnostic study |
| topic | cervical cancer screening cervical intraepithelial neoplasia colposcopy smartscopy covid-19 |
| url | http://ogscience.org/upload/pdf/ogs-22092.pdf |
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