Postoperative morbidity of complete mesocolic excision and central vascular ligation in right colectomy: a retrospective comparative cohort study
Abstract Background To investigate morbidity and mortality following complete mesocolic excision (CME) and central vascular ligation (CVL) in patients undergoing right colectomy. Methods Data from consecutive patients undergoing elective right colectomy at a university-affiliated referral centre wer...
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| Format: | Article |
| Language: | English |
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BMC
2018-10-01
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| Series: | World Journal of Surgical Oncology |
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| Online Access: | http://link.springer.com/article/10.1186/s12957-018-1514-3 |
| _version_ | 1818851100664528896 |
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| author | Gian Andrea Prevost Manfred Odermatt Markus Furrer Peter Villiger |
| author_facet | Gian Andrea Prevost Manfred Odermatt Markus Furrer Peter Villiger |
| author_sort | Gian Andrea Prevost |
| collection | DOAJ |
| description | Abstract Background To investigate morbidity and mortality following complete mesocolic excision (CME) and central vascular ligation (CVL) in patients undergoing right colectomy. Methods Data from consecutive patients undergoing elective right colectomy at a university-affiliated referral centre were retrospectively analysed. Patients who underwent conventional right-sided colonic cancer surgery (January 2001–April 2009, n = 84) were compared to patients who underwent CME/CVL (May 2009–January 2015, n = 71). The primary end point was anastomotic leak. Secondary end points were delayed gastric emptying, severe respiratory failure, mortality and length of hospital stay. Results No significant difference was found in the rate of anastomotic leak (1.2% in the conventional versus 5.6% in the CME/CVL group, p = 0.108). Patients in the CME/CVL group had a higher 90-day mortality rate (7.0% versus 0.0%, p = 0.019). Four out of five deceased patients suffered from aspiration with consecutive respiratory failure. There was a tendency towards delayed gastric emptying in the CME/CVL group (12.7% versus 7.1%, p = 0.246). Clavien-Dindo complication grades ≥ 2 were similar in both groups with 16 (19%) in the conventional and 15 (21.1%) in the CME/CVL group (p = 0.747). CME/CVL patients had a shorter mean length of stay with 11 versus 14 days (p < 0.001). Conclusions Complete mesocolic excision with central vascular ligation in right colectomy seems to have a higher aspiration rate leading to severe respiratory failure and to higher mortality compared to conventional resection methods. Patient selection for this procedure may therefore be crucial. |
| first_indexed | 2024-12-19T06:59:40Z |
| format | Article |
| id | doaj.art-0513bc1a1da24505afda916506f10039 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-12-19T06:59:40Z |
| publishDate | 2018-10-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-0513bc1a1da24505afda916506f100392022-12-21T20:31:27ZengBMCWorld Journal of Surgical Oncology1477-78192018-10-011611810.1186/s12957-018-1514-3Postoperative morbidity of complete mesocolic excision and central vascular ligation in right colectomy: a retrospective comparative cohort studyGian Andrea Prevost0Manfred Odermatt1Markus Furrer2Peter Villiger3Department of Surgery, Kantonsspital GraubündenDepartment of Surgery, Kantonsspital GraubündenDepartment of Surgery, Kantonsspital GraubündenDepartment of Surgery, Kantonsspital GraubündenAbstract Background To investigate morbidity and mortality following complete mesocolic excision (CME) and central vascular ligation (CVL) in patients undergoing right colectomy. Methods Data from consecutive patients undergoing elective right colectomy at a university-affiliated referral centre were retrospectively analysed. Patients who underwent conventional right-sided colonic cancer surgery (January 2001–April 2009, n = 84) were compared to patients who underwent CME/CVL (May 2009–January 2015, n = 71). The primary end point was anastomotic leak. Secondary end points were delayed gastric emptying, severe respiratory failure, mortality and length of hospital stay. Results No significant difference was found in the rate of anastomotic leak (1.2% in the conventional versus 5.6% in the CME/CVL group, p = 0.108). Patients in the CME/CVL group had a higher 90-day mortality rate (7.0% versus 0.0%, p = 0.019). Four out of five deceased patients suffered from aspiration with consecutive respiratory failure. There was a tendency towards delayed gastric emptying in the CME/CVL group (12.7% versus 7.1%, p = 0.246). Clavien-Dindo complication grades ≥ 2 were similar in both groups with 16 (19%) in the conventional and 15 (21.1%) in the CME/CVL group (p = 0.747). CME/CVL patients had a shorter mean length of stay with 11 versus 14 days (p < 0.001). Conclusions Complete mesocolic excision with central vascular ligation in right colectomy seems to have a higher aspiration rate leading to severe respiratory failure and to higher mortality compared to conventional resection methods. Patient selection for this procedure may therefore be crucial.http://link.springer.com/article/10.1186/s12957-018-1514-3Right colectomyComplete mesocolic excisionCentral vascular ligationMorbidityMortality |
| spellingShingle | Gian Andrea Prevost Manfred Odermatt Markus Furrer Peter Villiger Postoperative morbidity of complete mesocolic excision and central vascular ligation in right colectomy: a retrospective comparative cohort study World Journal of Surgical Oncology Right colectomy Complete mesocolic excision Central vascular ligation Morbidity Mortality |
| title | Postoperative morbidity of complete mesocolic excision and central vascular ligation in right colectomy: a retrospective comparative cohort study |
| title_full | Postoperative morbidity of complete mesocolic excision and central vascular ligation in right colectomy: a retrospective comparative cohort study |
| title_fullStr | Postoperative morbidity of complete mesocolic excision and central vascular ligation in right colectomy: a retrospective comparative cohort study |
| title_full_unstemmed | Postoperative morbidity of complete mesocolic excision and central vascular ligation in right colectomy: a retrospective comparative cohort study |
| title_short | Postoperative morbidity of complete mesocolic excision and central vascular ligation in right colectomy: a retrospective comparative cohort study |
| title_sort | postoperative morbidity of complete mesocolic excision and central vascular ligation in right colectomy a retrospective comparative cohort study |
| topic | Right colectomy Complete mesocolic excision Central vascular ligation Morbidity Mortality |
| url | http://link.springer.com/article/10.1186/s12957-018-1514-3 |
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