Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases

Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases

Abstract Background Tissue organoids generated from human pluripotent stem cells are valuable tools for disease modelling and to understand developmental processes. While recent progress in human cardiac organoids revealed the ability of these stem cell-derived organoids to self-organize and intrins...

Full description

Bibliographic Details
Main Authors: Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Ying Chen, Yuin-Han Loh, Omer An, Henry He Yang, Veerabrahma Pratap Seshachalam, Judice L. Y. Koh, Woon-Khiong Chan, Shi Yan Ng, Boon Seng Soh
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Stem Cell Research & Therapy
Subjects:
Cardiac progenitor
Chambered cardiac organoid
Disease modelling
Human pluripotent stem cells
Single-cell RNA sequencing
Online Access:https://doi.org/10.1186/s13287-022-03215-1

Similar Items

Similar Items