The selective estrogen receptor modulator raloxifene inhibits neutrophil extracellular trap formation.

The selective estrogen receptor modulator raloxifene inhibits neutrophil extracellular trap formation.

Raloxifene is a selective estrogen receptor modulator typically prescribed for the prevention/treatment of osteoporosis in postmenopausal women. Although raloxifene is known to have anti-inflammatory properties, its effect on human neutrophils, the primary phagocytic leukocytes of the immune system,...

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Bibliographic Details
Main Authors: Roxana Flores, Simon Döhrmann, Christina Schaal, Abdul Hakkim, Victor Nizet, Ross Corriden
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Immunology
Subjects:
Host-Pathogen Interactions
Neutrophils
Raloxifene
MRSA
extracellular traps
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00566/full

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