Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS)
Deep brain stimulation (DBS) is an effective and safe medical treatment that improves the lives of patients with a wide range of neurological and psychiatric diseases, and has been consolidated as a first-line tool in the last two decades. Closed-loop deep brain stimulation (CLDBS) pushes this tool...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Electronics |
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| Online Access: | https://www.mdpi.com/2079-9292/12/14/3082 |
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| author | Tiago Matheus Nordi Gabriel Augusto Ginja Rodrigo Gounella Erich Talanoni Fonoff Eduardo Colombari Melkzedekue M. Alcântara Moreira Jose A. Afonso Vitor Monteiro Joao L. Afonso João Paulo Carmo |
| author_facet | Tiago Matheus Nordi Gabriel Augusto Ginja Rodrigo Gounella Erich Talanoni Fonoff Eduardo Colombari Melkzedekue M. Alcântara Moreira Jose A. Afonso Vitor Monteiro Joao L. Afonso João Paulo Carmo |
| author_sort | Tiago Matheus Nordi |
| collection | DOAJ |
| description | Deep brain stimulation (DBS) is an effective and safe medical treatment that improves the lives of patients with a wide range of neurological and psychiatric diseases, and has been consolidated as a first-line tool in the last two decades. Closed-loop deep brain stimulation (CLDBS) pushes this tool further by automatically adjusting the stimulation parameters to the brain response in real time. The main contribution of this paper is a low-size/power-controlled, compact and complete CLDBS system with two simultaneous acquisition channels, two simultaneous neurostimulation channels and wireless communication. Each channel has a low-noise amplifier (LNA) buffer in differential configuration to eliminate the DC signal component of the input. Energy management is efficiently done by the control and communication unit. The battery supports almost 9 h with both the acquisition and stimulation circuits active. If only the stimulation circuit is used as an Open Loop DBS, the battery can hold sufficient voltage for 24 h of operation. The whole system is low-cost and portable and therefore it could be used as a wearable device. |
| first_indexed | 2024-03-11T01:07:19Z |
| format | Article |
| id | doaj.art-051921912337477eb62eb769e89c1bd3 |
| institution | Directory Open Access Journal |
| issn | 2079-9292 |
| language | English |
| last_indexed | 2024-03-11T01:07:19Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Electronics |
| spelling | doaj.art-051921912337477eb62eb769e89c1bd32023-11-18T19:05:34ZengMDPI AGElectronics2079-92922023-07-011214308210.3390/electronics12143082Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS)Tiago Matheus Nordi0Gabriel Augusto Ginja1Rodrigo Gounella2Erich Talanoni Fonoff3Eduardo Colombari4Melkzedekue M. Alcântara Moreira5Jose A. Afonso6Vitor Monteiro7Joao L. Afonso8João Paulo Carmo9Group of Metamaterials Microwaves and Optics (GMeta), Department of Electrical Engineering (SEL), University of São Paulo (USP), Avenida Trabalhador São-Carlense, Nr. 400, Parque Industrial Arnold Schimidt, São Carlos CEP 13566-590, SP, BrazilGroup of Metamaterials Microwaves and Optics (GMeta), Department of Electrical Engineering (SEL), University of São Paulo (USP), Avenida Trabalhador São-Carlense, Nr. 400, Parque Industrial Arnold Schimidt, São Carlos CEP 13566-590, SP, BrazilGroup of Metamaterials Microwaves and Optics (GMeta), Department of Electrical Engineering (SEL), University of São Paulo (USP), Avenida Trabalhador São-Carlense, Nr. 400, Parque Industrial Arnold Schimidt, São Carlos CEP 13566-590, SP, BrazilDepartment of Neurology, Faculty of Medicine, Avenida Dr. Arnaldo, Nr. 455, Cerqueira César, São Paulo CEP 01246-903, SP, BrazilDepartment of Physiology and Pathology, Faculty of Odontology, São Paulo State University (UNESP), Rua Humaitá, Nr. 1680, Araraquara CEP 14801-385, SP, BrazilDepartment of Mechancial Engineering (SEM), University of São Paulo (USP), Avenida Trabalhador São-Carlense, Nr. 400, Parque Industrial Arnold Schimidt, São Carlos CEP 13566-590, SP, BrazilCMEMS-UMinho, University of Minho, 4800-058 Guimarães, PortugalALGORITMI Research Centre/LASI, University of Minho, 4800-058 Guimarães, PortugalALGORITMI Research Centre/LASI, University of Minho, 4800-058 Guimarães, PortugalGroup of Metamaterials Microwaves and Optics (GMeta), Department of Electrical Engineering (SEL), University of São Paulo (USP), Avenida Trabalhador São-Carlense, Nr. 400, Parque Industrial Arnold Schimidt, São Carlos CEP 13566-590, SP, BrazilDeep brain stimulation (DBS) is an effective and safe medical treatment that improves the lives of patients with a wide range of neurological and psychiatric diseases, and has been consolidated as a first-line tool in the last two decades. Closed-loop deep brain stimulation (CLDBS) pushes this tool further by automatically adjusting the stimulation parameters to the brain response in real time. The main contribution of this paper is a low-size/power-controlled, compact and complete CLDBS system with two simultaneous acquisition channels, two simultaneous neurostimulation channels and wireless communication. Each channel has a low-noise amplifier (LNA) buffer in differential configuration to eliminate the DC signal component of the input. Energy management is efficiently done by the control and communication unit. The battery supports almost 9 h with both the acquisition and stimulation circuits active. If only the stimulation circuit is used as an Open Loop DBS, the battery can hold sufficient voltage for 24 h of operation. The whole system is low-cost and portable and therefore it could be used as a wearable device.https://www.mdpi.com/2079-9292/12/14/3082closed-loop deep brain stimulation (CLDBS)neurostimulationimplantable devicesinternet of things (IoT)energy management |
| spellingShingle | Tiago Matheus Nordi Gabriel Augusto Ginja Rodrigo Gounella Erich Talanoni Fonoff Eduardo Colombari Melkzedekue M. Alcântara Moreira Jose A. Afonso Vitor Monteiro Joao L. Afonso João Paulo Carmo Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS) Electronics closed-loop deep brain stimulation (CLDBS) neurostimulation implantable devices internet of things (IoT) energy management |
| title | Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS) |
| title_full | Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS) |
| title_fullStr | Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS) |
| title_full_unstemmed | Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS) |
| title_short | Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS) |
| title_sort | wireless device with energy management for closed loop deep brain stimulation cldbs |
| topic | closed-loop deep brain stimulation (CLDBS) neurostimulation implantable devices internet of things (IoT) energy management |
| url | https://www.mdpi.com/2079-9292/12/14/3082 |
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