A pilot study investigating the effects of voluntary exercise on capillary stalling and cerebral blood flow in the APP/PS1 mouse model of Alzheimer's disease.

Exercise exerts a beneficial effect on the major pathological and clinical symptoms associated with Alzheimer's disease in humans and mouse models of the disease. While numerous mechanisms for such benefits from exercise have been proposed, a clear understanding of the causal links remains elus...

Full description

Bibliographic Details
Main Authors: Kaja Falkenhain, Nancy E Ruiz-Uribe, Mohammad Haft-Javaherian, Muhammad Ali, Stall Catchers, Pietro E Michelucci, Chris B Schaffer, Oliver Bracko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0235691