Effect of the pseudomonas metabolites HQNO on the Toxoplasma gondii RH strain in vitro and in vivo

Effect of the pseudomonas metabolites HQNO on the Toxoplasma gondii RH strain in vitro and in vivo

Toxoplasmosis is a widespread disease in humans and animals. Currently, toxoplasmosis chemotherapy options are limited due to severe side effects. There is an urgent need to develop new drugs with better efficacy and few side effects. HQNO, a cytochrome bc1 and type II NADH inhibitor in eukaryotes a...

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Bibliographic Details
Main Authors: Jiao Mo, Hongfei Si, Siyang Liu, Qingyuan Zeng, Minghao Cai, Zhendi Liu, Jiyu Zhang, Jingjing Fang, Jili Zhang
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
HQNO
Toxoplasma gondii
Invasion
Proliferation
Pharmacokinetics
In vivo
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320723000052

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