Implementation of the plasma MYCN/NAGK ratio to detect MYCN amplification in patients with neuroblastoma

Implementation of the plasma MYCN/NAGK ratio to detect MYCN amplification in patients with neuroblastoma

Detection of amplification of the MYCN gene is essential for determining optimal treatment and estimating prognosis of patients with neuroblastoma (NB). DNA FISH with neuroblastoma tissues or patient‐derived bone marrow cells is the standard clinical practice for the detection of MYCN amplification....

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Bibliographic Details
Main Authors: Yan Su, Lijun Wang, Qian Zhao, Zhixia Yue, Wen Zhao, Xisi Wang, Chao Duan, Mei Jin, Dawei Zhang, Shenglan Chen, Jianfeng Yin, Lihua Qiu, Xianfeng Cheng, Zhong Xu, Xiaoli Ma
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:Molecular Oncology
Subjects:
MYCN amplification
MYCN/NAGK ratio
neuroblastoma
plasma
qPCR
Online Access:https://doi.org/10.1002/1878-0261.12794

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