circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis

circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis

Abstract Objective Osteoporosis is the imbalance in bone homeostasis between osteoblasts and osteoclasts. In this study, we investigated the effects of the circ_0029463/miR-134-5p/Rab27a axis on RANKL-induced osteoclast differentiation. Methods RT-qPCR and western blotting were used to detect the ex...

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Bibliographic Details
Main Authors: Lian Tang, Lin Yuan, Jiyuan Yan, Jianhua Ge, Zhi Lian, Zhong Li
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
circ_0029463
miR-134-5p
Rab27a
Osteoclast differentiation
Online Access:https://doi.org/10.1186/s13018-024-04610-5

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