Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology

Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology

Leptospira spp. are diderm (two membranes) bacteria that infect mammals causing leptospirosis, a public health problem with global implications. Thousands of people die every year due to leptospirosis, especially in developing countries with tropical climates. Prophylaxis is difficult due to multipl...

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Bibliographic Details
Main Authors:	Alan John Alexander McBride, André Alex Grassmann, Frederico Schmitt Kremer, Júlia Cougo dos Santos, Jéssica Dias Souza, Luciano da Silva Pinto
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-04-01
Series:	Frontiers in Immunology
Subjects:	Leptospira interrogans outer membrane protein epitope prediction bioinformatics transport proteins structural modeling
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00463/full

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