Conjunctival Goblet Cell Responses to TLR5 Engagement Promote Activation of Local Antigen-Presenting Cells

Conjunctival Goblet Cell Responses to TLR5 Engagement Promote Activation of Local Antigen-Presenting Cells

Conjunctival epithelium forms a barrier between the ocular surface microbial flora and the ocular mucosa. In addition to secreting gel-forming mucins, goblet cells, located in the conjunctival epithelium, help maintain local immune homeostasis by secreting active TGFβ2 and promoting tolerogenic phen...

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Bibliographic Details
Main Authors: Abiramy Logeswaran, Laura Contreras-Ruiz, Sharmila Masli
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
conjunctiva
ocular mucosa
goblet cells
homeostasis
dendritic cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.716939/full

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