Septic shock due to co-infection with Legionella pneumophila and Saprochaete clavata

Septic shock is the most dreaded presentation of an infection, carrying a reserved prognosis. Appropriate antimicrobial therapy is therefore the mainstay of treatment, alongside organ support as needed. Legionnaires’ disease is mainly due to Legionella pneumophila serogroup 1 but it can be caused by...

Full description

Bibliographic Details
Main Authors: João Paulo Caldas, André Silva-Pinto, Ana Sofia Faustino, Paulo Figueiredo, António Sarmento, Lurdes Santos
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:IDCases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250921003255
_version_ 1818289300701184000
author João Paulo Caldas
André Silva-Pinto
Ana Sofia Faustino
Paulo Figueiredo
António Sarmento
Lurdes Santos
author_facet João Paulo Caldas
André Silva-Pinto
Ana Sofia Faustino
Paulo Figueiredo
António Sarmento
Lurdes Santos
author_sort João Paulo Caldas
collection DOAJ
description Septic shock is the most dreaded presentation of an infection, carrying a reserved prognosis. Appropriate antimicrobial therapy is therefore the mainstay of treatment, alongside organ support as needed. Legionnaires’ disease is mainly due to Legionella pneumophila serogroup 1 but it can be caused by other serogroups and species not detected by the urinary antigen test. Anti-tumour necrosis factor α therapy may increase the risk of invasive fungal infection, which carry a poor prognosis. We present a challenging case of a septic shock due to Legionella pneumophila and Saprochaete clavata infections, with a review of the two infections presented.
first_indexed 2024-12-13T02:10:05Z
format Article
id doaj.art-0533ff16216643cf96a00caee1583681
institution Directory Open Access Journal
issn 2214-2509
language English
last_indexed 2024-12-13T02:10:05Z
publishDate 2022-01-01
publisher Elsevier
record_format Article
series IDCases
spelling doaj.art-0533ff16216643cf96a00caee15836812022-12-22T00:03:02ZengElsevierIDCases2214-25092022-01-0127e01369Septic shock due to co-infection with Legionella pneumophila and Saprochaete clavataJoão Paulo Caldas0André Silva-Pinto1Ana Sofia Faustino2Paulo Figueiredo3António Sarmento4Lurdes Santos5Correspondence to: Infectious Diseases Department, Centro Hospitalar Universitário de São João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.; Infectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, PortugalInfectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, PortugalInfectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, PortugalInfectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, PortugalInfectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, PortugalInfectious Diseases Department of Centro Hospitalar Universitário de São João, Oporto, PortugalSeptic shock is the most dreaded presentation of an infection, carrying a reserved prognosis. Appropriate antimicrobial therapy is therefore the mainstay of treatment, alongside organ support as needed. Legionnaires’ disease is mainly due to Legionella pneumophila serogroup 1 but it can be caused by other serogroups and species not detected by the urinary antigen test. Anti-tumour necrosis factor α therapy may increase the risk of invasive fungal infection, which carry a poor prognosis. We present a challenging case of a septic shock due to Legionella pneumophila and Saprochaete clavata infections, with a review of the two infections presented.http://www.sciencedirect.com/science/article/pii/S2214250921003255Legionnaires’ diseaseSaprochaete clavataAnti-TNF-α therapyExtracorporeal membrane oxygenationRenal replacement therapyPlasmapheresis
spellingShingle João Paulo Caldas
André Silva-Pinto
Ana Sofia Faustino
Paulo Figueiredo
António Sarmento
Lurdes Santos
Septic shock due to co-infection with Legionella pneumophila and Saprochaete clavata
IDCases
Legionnaires’ disease
Saprochaete clavata
Anti-TNF-α therapy
Extracorporeal membrane oxygenation
Renal replacement therapy
Plasmapheresis
title Septic shock due to co-infection with Legionella pneumophila and Saprochaete clavata
title_full Septic shock due to co-infection with Legionella pneumophila and Saprochaete clavata
title_fullStr Septic shock due to co-infection with Legionella pneumophila and Saprochaete clavata
title_full_unstemmed Septic shock due to co-infection with Legionella pneumophila and Saprochaete clavata
title_short Septic shock due to co-infection with Legionella pneumophila and Saprochaete clavata
title_sort septic shock due to co infection with legionella pneumophila and saprochaete clavata
topic Legionnaires’ disease
Saprochaete clavata
Anti-TNF-α therapy
Extracorporeal membrane oxygenation
Renal replacement therapy
Plasmapheresis
url http://www.sciencedirect.com/science/article/pii/S2214250921003255
work_keys_str_mv AT joaopaulocaldas septicshockduetocoinfectionwithlegionellapneumophilaandsaprochaeteclavata
AT andresilvapinto septicshockduetocoinfectionwithlegionellapneumophilaandsaprochaeteclavata
AT anasofiafaustino septicshockduetocoinfectionwithlegionellapneumophilaandsaprochaeteclavata
AT paulofigueiredo septicshockduetocoinfectionwithlegionellapneumophilaandsaprochaeteclavata
AT antoniosarmento septicshockduetocoinfectionwithlegionellapneumophilaandsaprochaeteclavata
AT lurdessantos septicshockduetocoinfectionwithlegionellapneumophilaandsaprochaeteclavata