Unlocking the Real Potential of Black Soldier Fly (<i>Hermetia illucens</i>) Larvae Protein Derivatives in Pet Diets
Black soldier fly larvae (BSFL)-derived proteins are gaining popularity as sustainable pet food ingredients. According to the literature, these ingredients have strong antioxidant and antimicrobial activities. Due to the ability of BSFL protein derivatives to donate hydrogen atoms and/or electrons t...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-07-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/14/4216 |
| _version_ | 1797526494621204480 |
|---|---|
| author | Ange Mouithys-Mickalad Nuria Martin Tome Thomas Boogaard Arpita Chakraborty Didier Serteyn Kees Aarts Aman Paul |
| author_facet | Ange Mouithys-Mickalad Nuria Martin Tome Thomas Boogaard Arpita Chakraborty Didier Serteyn Kees Aarts Aman Paul |
| author_sort | Ange Mouithys-Mickalad |
| collection | DOAJ |
| description | Black soldier fly larvae (BSFL)-derived proteins are gaining popularity as sustainable pet food ingredients. According to the literature, these ingredients have strong antioxidant and antimicrobial activities. Due to the ability of BSFL protein derivatives to donate hydrogen atoms and/or electrons to counterpoise unstable molecules, they could possibly help in the prevention of osteoarthritis. During this study, the antiarthritic potential of BSFL protein derivatives was evaluated using the following assays: (1) proteinase inhibition, (2) erythrocyte membrane stability, (3) reactive oxygen species (ROS) production by activated macrophages, (4) ROS production by monocytes, and (5) cellular toxicity. Additionally, the glucosamine content of these ingredients was also evaluated. Chicken meal is commonly used in pet food formulations and was used as an industrial benchmark. The results obtained during this study demonstrated the strong antiarthritic potential of BSFL protein derivatives. We found that BSFL protein derivatives are not only useful in preventing the development of arthritis but could also help to cure it due to the presence of glucosamine. We also found that chicken meal could contribute to the development of arthritis by increasing ROS production by monocytes. |
| first_indexed | 2024-03-10T09:30:07Z |
| format | Article |
| id | doaj.art-0537809976f449af8571f1e0b6999dee |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T09:30:07Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-0537809976f449af8571f1e0b6999dee2023-11-22T04:30:22ZengMDPI AGMolecules1420-30492021-07-012614421610.3390/molecules26144216Unlocking the Real Potential of Black Soldier Fly (<i>Hermetia illucens</i>) Larvae Protein Derivatives in Pet DietsAnge Mouithys-Mickalad0Nuria Martin Tome1Thomas Boogaard2Arpita Chakraborty3Didier Serteyn4Kees Aarts5Aman Paul6Centre of Oxygen, Research and Development, University of Liege, 4000 Liege, BelgiumProtix B.V., 5107 NC Dongen, The NetherlandsNutrilab B.V., 4283 GG Giessen, The NetherlandsProtix B.V., 5107 NC Dongen, The NetherlandsCentre of Oxygen, Research and Development, University of Liege, 4000 Liege, BelgiumProtix B.V., 5107 NC Dongen, The NetherlandsProtix B.V., 5107 NC Dongen, The NetherlandsBlack soldier fly larvae (BSFL)-derived proteins are gaining popularity as sustainable pet food ingredients. According to the literature, these ingredients have strong antioxidant and antimicrobial activities. Due to the ability of BSFL protein derivatives to donate hydrogen atoms and/or electrons to counterpoise unstable molecules, they could possibly help in the prevention of osteoarthritis. During this study, the antiarthritic potential of BSFL protein derivatives was evaluated using the following assays: (1) proteinase inhibition, (2) erythrocyte membrane stability, (3) reactive oxygen species (ROS) production by activated macrophages, (4) ROS production by monocytes, and (5) cellular toxicity. Additionally, the glucosamine content of these ingredients was also evaluated. Chicken meal is commonly used in pet food formulations and was used as an industrial benchmark. The results obtained during this study demonstrated the strong antiarthritic potential of BSFL protein derivatives. We found that BSFL protein derivatives are not only useful in preventing the development of arthritis but could also help to cure it due to the presence of glucosamine. We also found that chicken meal could contribute to the development of arthritis by increasing ROS production by monocytes.https://www.mdpi.com/1420-3049/26/14/4216<i>Hermetia illucens</i>chicken mealarthritispetsproteinaseerythrocytes |
| spellingShingle | Ange Mouithys-Mickalad Nuria Martin Tome Thomas Boogaard Arpita Chakraborty Didier Serteyn Kees Aarts Aman Paul Unlocking the Real Potential of Black Soldier Fly (<i>Hermetia illucens</i>) Larvae Protein Derivatives in Pet Diets Molecules <i>Hermetia illucens</i> chicken meal arthritis pets proteinase erythrocytes |
| title | Unlocking the Real Potential of Black Soldier Fly (<i>Hermetia illucens</i>) Larvae Protein Derivatives in Pet Diets |
| title_full | Unlocking the Real Potential of Black Soldier Fly (<i>Hermetia illucens</i>) Larvae Protein Derivatives in Pet Diets |
| title_fullStr | Unlocking the Real Potential of Black Soldier Fly (<i>Hermetia illucens</i>) Larvae Protein Derivatives in Pet Diets |
| title_full_unstemmed | Unlocking the Real Potential of Black Soldier Fly (<i>Hermetia illucens</i>) Larvae Protein Derivatives in Pet Diets |
| title_short | Unlocking the Real Potential of Black Soldier Fly (<i>Hermetia illucens</i>) Larvae Protein Derivatives in Pet Diets |
| title_sort | unlocking the real potential of black soldier fly i hermetia illucens i larvae protein derivatives in pet diets |
| topic | <i>Hermetia illucens</i> chicken meal arthritis pets proteinase erythrocytes |
| url | https://www.mdpi.com/1420-3049/26/14/4216 |
| work_keys_str_mv | AT angemouithysmickalad unlockingtherealpotentialofblacksoldierflyihermetiaillucensilarvaeproteinderivativesinpetdiets AT nuriamartintome unlockingtherealpotentialofblacksoldierflyihermetiaillucensilarvaeproteinderivativesinpetdiets AT thomasboogaard unlockingtherealpotentialofblacksoldierflyihermetiaillucensilarvaeproteinderivativesinpetdiets AT arpitachakraborty unlockingtherealpotentialofblacksoldierflyihermetiaillucensilarvaeproteinderivativesinpetdiets AT didierserteyn unlockingtherealpotentialofblacksoldierflyihermetiaillucensilarvaeproteinderivativesinpetdiets AT keesaarts unlockingtherealpotentialofblacksoldierflyihermetiaillucensilarvaeproteinderivativesinpetdiets AT amanpaul unlockingtherealpotentialofblacksoldierflyihermetiaillucensilarvaeproteinderivativesinpetdiets |