Effects of Aronia melanocarpa Constituents on Biofilm Formation of Escherichia coli and Bacillus cereus
Many bacteria growing on surfaces form biofilms. Adaptive and genetic changes of the microorganisms in this structure make them resistant to antimicrobial agents. Biofilm-forming organisms on medical devices can pose serious threats to human health. Thus, there is a need for novel prevention and tre...
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| Format: | Article |
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MDPI AG
2013-12-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/18/12/14989 |
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| author | Marie Bräunlich Ole A. Økstad Rune Slimestad Helle Wangensteen Karl E. Malterud Hilde Barsett |
| author_facet | Marie Bräunlich Ole A. Økstad Rune Slimestad Helle Wangensteen Karl E. Malterud Hilde Barsett |
| author_sort | Marie Bräunlich |
| collection | DOAJ |
| description | Many bacteria growing on surfaces form biofilms. Adaptive and genetic changes of the microorganisms in this structure make them resistant to antimicrobial agents. Biofilm-forming organisms on medical devices can pose serious threats to human health. Thus, there is a need for novel prevention and treatment strategies. This study aimed to evaluate the ability of Aronia melanocarpa extracts, subfractions and compounds to prevent biofilm formation and to inhibit bacterial growth of Escherichia coli and Bacillus cereus in vitro. It was found that several aronia substances possessed anti-biofilm activity, however, they were not toxic to the species screened. This non-toxic inhibition may confer a lower potential for resistance development compared to conventional antimicrobials. |
| first_indexed | 2024-12-20T10:02:34Z |
| format | Article |
| id | doaj.art-053eb19048064f60b619d32128e3f6da |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-20T10:02:34Z |
| publishDate | 2013-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-053eb19048064f60b619d32128e3f6da2022-12-21T19:44:18ZengMDPI AGMolecules1420-30492013-12-011812149891499910.3390/molecules181214989molecules181214989Effects of Aronia melanocarpa Constituents on Biofilm Formation of Escherichia coli and Bacillus cereusMarie Bräunlich0Ole A. Økstad1Rune Slimestad2Helle Wangensteen3Karl E. Malterud4Hilde Barsett5Department of Pharmaceutical Chemistry, School of Pharmacy, University of Oslo, P.O. Box 1068, Blindern, Oslo N-0316, NorwayLaboratory for Microbial Dynamics and Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, P.O. Box 1068, Blindern, Oslo N-0316, NorwayPlantChem, Særheim Research Center, N-4353 Klepp Station, NorwayDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of Oslo, P.O. Box 1068, Blindern, Oslo N-0316, NorwayDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of Oslo, P.O. Box 1068, Blindern, Oslo N-0316, NorwayDepartment of Pharmaceutical Chemistry, School of Pharmacy, University of Oslo, P.O. Box 1068, Blindern, Oslo N-0316, NorwayMany bacteria growing on surfaces form biofilms. Adaptive and genetic changes of the microorganisms in this structure make them resistant to antimicrobial agents. Biofilm-forming organisms on medical devices can pose serious threats to human health. Thus, there is a need for novel prevention and treatment strategies. This study aimed to evaluate the ability of Aronia melanocarpa extracts, subfractions and compounds to prevent biofilm formation and to inhibit bacterial growth of Escherichia coli and Bacillus cereus in vitro. It was found that several aronia substances possessed anti-biofilm activity, however, they were not toxic to the species screened. This non-toxic inhibition may confer a lower potential for resistance development compared to conventional antimicrobials.http://www.mdpi.com/1420-3049/18/12/14989Aronia melanocarpabiofilm formationEscherichia coliBacillus cereusflavonoids |
| spellingShingle | Marie Bräunlich Ole A. Økstad Rune Slimestad Helle Wangensteen Karl E. Malterud Hilde Barsett Effects of Aronia melanocarpa Constituents on Biofilm Formation of Escherichia coli and Bacillus cereus Molecules Aronia melanocarpa biofilm formation Escherichia coli Bacillus cereus flavonoids |
| title | Effects of Aronia melanocarpa Constituents on Biofilm Formation of Escherichia coli and Bacillus cereus |
| title_full | Effects of Aronia melanocarpa Constituents on Biofilm Formation of Escherichia coli and Bacillus cereus |
| title_fullStr | Effects of Aronia melanocarpa Constituents on Biofilm Formation of Escherichia coli and Bacillus cereus |
| title_full_unstemmed | Effects of Aronia melanocarpa Constituents on Biofilm Formation of Escherichia coli and Bacillus cereus |
| title_short | Effects of Aronia melanocarpa Constituents on Biofilm Formation of Escherichia coli and Bacillus cereus |
| title_sort | effects of aronia melanocarpa constituents on biofilm formation of escherichia coli and bacillus cereus |
| topic | Aronia melanocarpa biofilm formation Escherichia coli Bacillus cereus flavonoids |
| url | http://www.mdpi.com/1420-3049/18/12/14989 |
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