STING protects against cardiac dysfunction and remodelling by blocking autophagy

STING protects against cardiac dysfunction and remodelling by blocking autophagy

Abstract Background Heart failure, which is characterized by cardiac remodelling, is one of the most common chronic diseases in the aged. Stimulator of interferon genes (STING) acts as an indispensable molecule modulating immune response and inflammation in many diseases. However, the effects of STI...

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Bibliographic Details
Main Authors: Rui Xiong, Ning Li, Lei Chen, Wei Wang, Bo Wang, Wenyang Jiang, Qing Geng
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Cell Communication and Signaling
Subjects:
STING
Cardiac remodelling
Inflammation
Autophagy
ULK1
Online Access:https://doi.org/10.1186/s12964-021-00793-0

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