Advanced prostatic carcinomas with low serum levels of prostate-specific antigen
The serum levels of prostate-specific antigen (PSA) represent a significant diagnostic and monitoring parameter of prostatic carcinoma (PC). The aim of the study was to establish correlation of serum PSA level in addition to grade, histological type, and clinical stage of PC in patients with normal...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2002-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500202137C.pdf |
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| author | Cerović Snežana J. Tatić Vujadin Dimitrijević Jovan Ilić Srbislav Milović Novak Aleksić Predrag Brajušković Goran R. |
| author_facet | Cerović Snežana J. Tatić Vujadin Dimitrijević Jovan Ilić Srbislav Milović Novak Aleksić Predrag Brajušković Goran R. |
| author_sort | Cerović Snežana J. |
| collection | DOAJ |
| description | The serum levels of prostate-specific antigen (PSA) represent a significant diagnostic and monitoring parameter of prostatic carcinoma (PC). The aim of the study was to establish correlation of serum PSA level in addition to grade, histological type, and clinical stage of PC in patients with normal or intermediary PSA serum level. In 37 untreated PC patients with preoperative serum PSA levels ranging between 0.1 and 9.6 ng/ml, paraffin-embedded tissue and serum samples were immunohistological studied and immunoassay for PSA was done. The most representative was poorly differentiated PC with D stage In serum samples from PC patients 27 (73.7%) normal (≤ 4.0 ng/ml), and 10 (27.3%) intermediate (4.1-10 ng/ml) PSA levels were found Immunohistochemistry, in 36 PC (97.3%) had demonstrated the expression of PSA. Our study results had shown low serum PSA levels in some patients with advanced poorly differentiated PC. |
| first_indexed | 2024-12-18T08:28:50Z |
| format | Article |
| id | doaj.art-05454c0fe770410986a43894faace5c5 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 |
| language | English |
| last_indexed | 2024-12-18T08:28:50Z |
| publishDate | 2002-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-05454c0fe770410986a43894faace5c52022-12-21T21:14:31ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502002-01-0159213714010.2298/VSP0202137CAdvanced prostatic carcinomas with low serum levels of prostate-specific antigenCerović Snežana J.Tatić VujadinDimitrijević JovanIlić SrbislavMilović NovakAleksić PredragBrajušković Goran R.The serum levels of prostate-specific antigen (PSA) represent a significant diagnostic and monitoring parameter of prostatic carcinoma (PC). The aim of the study was to establish correlation of serum PSA level in addition to grade, histological type, and clinical stage of PC in patients with normal or intermediary PSA serum level. In 37 untreated PC patients with preoperative serum PSA levels ranging between 0.1 and 9.6 ng/ml, paraffin-embedded tissue and serum samples were immunohistological studied and immunoassay for PSA was done. The most representative was poorly differentiated PC with D stage In serum samples from PC patients 27 (73.7%) normal (≤ 4.0 ng/ml), and 10 (27.3%) intermediate (4.1-10 ng/ml) PSA levels were found Immunohistochemistry, in 36 PC (97.3%) had demonstrated the expression of PSA. Our study results had shown low serum PSA levels in some patients with advanced poorly differentiated PC.http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500202137C.pdfprostatic neoplasmscarcinomaprostate-specific antigen |
| spellingShingle | Cerović Snežana J. Tatić Vujadin Dimitrijević Jovan Ilić Srbislav Milović Novak Aleksić Predrag Brajušković Goran R. Advanced prostatic carcinomas with low serum levels of prostate-specific antigen Vojnosanitetski Pregled prostatic neoplasms carcinoma prostate-specific antigen |
| title | Advanced prostatic carcinomas with low serum levels of prostate-specific antigen |
| title_full | Advanced prostatic carcinomas with low serum levels of prostate-specific antigen |
| title_fullStr | Advanced prostatic carcinomas with low serum levels of prostate-specific antigen |
| title_full_unstemmed | Advanced prostatic carcinomas with low serum levels of prostate-specific antigen |
| title_short | Advanced prostatic carcinomas with low serum levels of prostate-specific antigen |
| title_sort | advanced prostatic carcinomas with low serum levels of prostate specific antigen |
| topic | prostatic neoplasms carcinoma prostate-specific antigen |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2002/0042-84500202137C.pdf |
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