A general biochemical kinetics data fitting algorithm for quasi-steady-state detection
We develop a general algorithm for fitting the biochemical kinetics data. The developed algorithm searches and analyzes numerous minima. This approach allows us to analyze biochemical data without a priori quasi-steady-state assumptions. The algorithm allows us to treat the biochemical kinetics data...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Vilnius University Press
2016-12-01
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| Series: | Lietuvos Matematikos Rinkinys |
| Subjects: | |
| Online Access: | https://www.journals.vu.lt/LMR/article/view/14934 |
| _version_ | 1819046655845990400 |
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| author | Justinas V. Daugmaudis Audrius Laurynėnas Juozas Kulys Feliksas Ivanauskas |
| author_facet | Justinas V. Daugmaudis Audrius Laurynėnas Juozas Kulys Feliksas Ivanauskas |
| author_sort | Justinas V. Daugmaudis |
| collection | DOAJ |
| description | We develop a general algorithm for fitting the biochemical kinetics data. The developed algorithm searches and analyzes numerous minima. This approach allows us to analyze biochemical data without a priori quasi-steady-state assumptions. The algorithm allows us to treat the biochemical kinetics data that has varying degree of steadiness. We test the approach by analyzing experiment data from 4-nitrophenyl phosphate hydrolysis with alkaline phosphatase. |
| first_indexed | 2024-12-21T10:47:56Z |
| format | Article |
| id | doaj.art-0545ea7161854c139cbfe90489969263 |
| institution | Directory Open Access Journal |
| issn | 0132-2818 2335-898X |
| language | English |
| last_indexed | 2024-12-21T10:47:56Z |
| publishDate | 2016-12-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Lietuvos Matematikos Rinkinys |
| spelling | doaj.art-0545ea7161854c139cbfe904899692632022-12-21T19:06:44ZengVilnius University PressLietuvos Matematikos Rinkinys0132-28182335-898X2016-12-0157A10.15388/LMR.A.2016.03A general biochemical kinetics data fitting algorithm for quasi-steady-state detectionJustinas V. Daugmaudis0Audrius Laurynėnas1Juozas Kulys2Feliksas Ivanauskas3Vilnius UniversityVilnius UniversityVilnius UniversityVilnius UniversityWe develop a general algorithm for fitting the biochemical kinetics data. The developed algorithm searches and analyzes numerous minima. This approach allows us to analyze biochemical data without a priori quasi-steady-state assumptions. The algorithm allows us to treat the biochemical kinetics data that has varying degree of steadiness. We test the approach by analyzing experiment data from 4-nitrophenyl phosphate hydrolysis with alkaline phosphatase.https://www.journals.vu.lt/LMR/article/view/14934biochemical kineticsdifferential equationscurve fittingreaction rate constantsphosphatase4-nitrophenylphosphate |
| spellingShingle | Justinas V. Daugmaudis Audrius Laurynėnas Juozas Kulys Feliksas Ivanauskas A general biochemical kinetics data fitting algorithm for quasi-steady-state detection Lietuvos Matematikos Rinkinys biochemical kinetics differential equations curve fitting reaction rate constants phosphatase 4-nitrophenylphosphate |
| title | A general biochemical kinetics data fitting algorithm for quasi-steady-state detection |
| title_full | A general biochemical kinetics data fitting algorithm for quasi-steady-state detection |
| title_fullStr | A general biochemical kinetics data fitting algorithm for quasi-steady-state detection |
| title_full_unstemmed | A general biochemical kinetics data fitting algorithm for quasi-steady-state detection |
| title_short | A general biochemical kinetics data fitting algorithm for quasi-steady-state detection |
| title_sort | general biochemical kinetics data fitting algorithm for quasi steady state detection |
| topic | biochemical kinetics differential equations curve fitting reaction rate constants phosphatase 4-nitrophenylphosphate |
| url | https://www.journals.vu.lt/LMR/article/view/14934 |
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