A pathogenic variant in the uncharacterized RNF212B gene results in severe aneuploidy male infertility and repeated IVF failure

A pathogenic variant in the uncharacterized RNF212B gene results in severe aneuploidy male infertility and repeated IVF failure

Summary: Quantitative and qualitative spermatogenic impairments are major causes of men’s infertility. Although in vitro fertilization (IVF) is effective, some couples persistently fail to conceive. To identify causal variants in patients with severe male infertility factor and repeated IVF failures...

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Bibliographic Details
Main Authors: Moran Gershoni, Tslil Braun, Ron Hauser, Shimi Barda, Ofer Lehavi, Mira Malcov, Tsvia Frumkin, Yael Kalma, Shmuel Pietrokovski, Eli Arama, Sandra E. Kleiman
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:HGG Advances
Subjects:
Aneuploidy
IVF failures
Human infertility
RNF212B
Meiosis
Genome instability
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247723000210

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