Autophagy and Its Relationship to Epithelial to Mesenchymal Transition: When Autophagy Inhibition for Cancer Therapy Turns Counterproductive

Autophagy and Its Relationship to Epithelial to Mesenchymal Transition: When Autophagy Inhibition for Cancer Therapy Turns Counterproductive

The manipulation of autophagy for cancer therapy has gained recent interest in clinical settings. Although inhibition of autophagy is currently being used in clinical trials for the treatment of several malignancies, autophagy has been shown to have diverse implications for normal cell homeostasis,...

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Bibliographic Details
Main Authors: Guadalupe Rojas-Sanchez, Israel Cotzomi-Ortega, Nidia G. Pazos-Salazar, Julio Reyes-Leyva, Paola Maycotte
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Biology
Subjects:
autophagy
cancer
cancer therapy
EMT
Online Access:https://www.mdpi.com/2079-7737/8/4/71

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