Complexity of NAC Action as an Antidiabetic Agent: Opposing Effects of Oxidative and Reductive Stress on Insulin Secretion and Insulin Signaling
Dysregulated redox balance is involved in the pathogenesis of type 2 diabetes. While the benefit of antioxidants in neutralizing oxidative stress is well characterized, the potential harm of antioxidant-induced reductive stress is unclear. The aim of this study was to investigate the dose-dependent...
Main Authors: | Lital Argaev-Frenkel, Tovit Rosenzweig |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/6/2965 |
Similar Items
-
Redox Balance in Type 2 Diabetes: Therapeutic Potential and the Challenge of Antioxidant-Based Therapy
by: Lital Argaev-Frenkel, et al.
Published: (2023-04-01) -
The standardized Jamu pahitan, an Indonesian antidiabetic formulation, stimulating the glucose uptake and insulin secretion in the in-vitro models
by: Dwi Hartanti, et al.
Published: (2023-03-01) -
Effect of Lactate on Insulin Action in Rats
by: Muhidin Hamamdžić, et al.
Published: (2008-05-01) -
Glutathione in Protein Redox Modulation through S-Glutathionylation and S-Nitrosylation
by: Elena Kalinina, et al.
Published: (2021-01-01) -
S-Glutathionylation and S-Nitrosylation in Mitochondria: Focus on Homeostasis and Neurodegenerative Diseases
by: Sofia Vrettou, et al.
Published: (2022-12-01)