Autonomous bioluminescent expression of the bacterial luciferase gene cassette (lux) in a mammalian cell line.
The bacterial luciferase (lux) gene cassette consists of five genes (luxCDABE) whose protein products synergistically generate bioluminescent light signals exclusive of supplementary substrate additions or exogenous manipulations. Historically expressible only in prokaryotes, the lux operon was re-s...
Main Authors: | Dan M Close, Stacey S Patterson, Steven Ripp, Seung J Baek, John Sanseverino, Gary S Sayler |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-08-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2929204?pdf=render |
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