LAM Genes Contribute to Environmental Stress Tolerance but Sensibilize Yeast Cells to Azoles

LAM Genes Contribute to Environmental Stress Tolerance but Sensibilize Yeast Cells to Azoles

Lam proteins transport sterols between the membranes of different cellular compartments. In Saccharomyces cerevisiae, the LAM gene family consists of three pairs of paralogs. Because the function of paralogous genes can be redundant, the phenotypes of only a small number of LAM gene deletions have b...

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Bibliographic Details
Main Authors: Svyatoslav S. Sokolov, Margarita A. Vorobeva, Alexandra I. Smirnova, Ekaterina A. Smirnova, Nataliya I. Trushina, Kseniia V. Galkina, Fedor F. Severin, Dmitry A. Knorre
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
azoles
drug resistance
LAM genes
sterol
stress tolerance
yeast
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00038/full

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