Relationship between the mechanisms of atherosclerosis and prostate cancer: literature review
Cardiovascular disease and cancer remain the leading causes of hospitalization and death worldwide. Prostate cancer (PC) is one of the most common malignant diseases in men. Epidemiological studies have shown that the majority of patients with PC die not from cancer but from cardiovascular diseases,...
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| Format: | Article |
| Language: | English |
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Concilium Medicum
2023-06-01
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| Series: | КардиоСоматика |
| Subjects: | |
| Online Access: | https://cardiosomatics.orscience.ru/2221-7185/article/viewFile/195493/pdf |
| _version_ | 1797803436884885504 |
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| author | Svetlana A. Pomeshkina Olga L. Barbarash Evgeny V. Pomeshkin Andrey I. Bragin-Maltsev |
| author_facet | Svetlana A. Pomeshkina Olga L. Barbarash Evgeny V. Pomeshkin Andrey I. Bragin-Maltsev |
| author_sort | Svetlana A. Pomeshkina |
| collection | DOAJ |
| description | Cardiovascular disease and cancer remain the leading causes of hospitalization and death worldwide. Prostate cancer (PC) is one of the most common malignant diseases in men. Epidemiological studies have shown that the majority of patients with PC die not from cancer but from cardiovascular diseases, particularly coronary heart disease. In recent years, several studies have examined the relationship between atherosclerosis and PC, suggesting a stronger relationship than previously thought. Processing characteristics of the development and progression of both diseases include dysregulation of cell proliferation, oxidative stress, genetic changes, and inflammation. Despite conflicting data on the role of high cholesterol levels in the development of PC over the past decade, numerous studies have confirmed its importance in PC development and progression; meanwhile, statins have confirmed their value in reducing the risk of disease development and progression. The presented data confirm the need for a thorough assessment of cardiovascular risk factors, the presence of concomitant cardiovascular diseases in patients with PC, and the use of methods for the prevention and treatment of diseases associated with atherosclerosis to reduce cardiovascular risk and inhibit PC progression. |
| first_indexed | 2024-03-13T05:21:51Z |
| format | Article |
| id | doaj.art-0550a2a018444b23b14c81b8ea7020c2 |
| institution | Directory Open Access Journal |
| issn | 2221-7185 2658-5707 |
| language | English |
| last_indexed | 2024-03-13T05:21:51Z |
| publishDate | 2023-06-01 |
| publisher | Concilium Medicum |
| record_format | Article |
| series | КардиоСоматика |
| spelling | doaj.art-0550a2a018444b23b14c81b8ea7020c22023-06-15T12:41:16ZengConcilium MedicumКардиоСоматика2221-71852658-57072023-06-01141495810.17816/CS19549376531Relationship between the mechanisms of atherosclerosis and prostate cancer: literature reviewSvetlana A. Pomeshkina0https://orcid.org/0000-0003-3333-216XOlga L. Barbarash1https://orcid.org/0000-0002-4642-3610Evgeny V. Pomeshkin2https://orcid.org/0000-0002-5612-1878Andrey I. Bragin-Maltsev3https://orcid.org/0000-0001-7102-2408Research Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesKemerovo State UniversityKemerovo State Medical UniversityCardiovascular disease and cancer remain the leading causes of hospitalization and death worldwide. Prostate cancer (PC) is one of the most common malignant diseases in men. Epidemiological studies have shown that the majority of patients with PC die not from cancer but from cardiovascular diseases, particularly coronary heart disease. In recent years, several studies have examined the relationship between atherosclerosis and PC, suggesting a stronger relationship than previously thought. Processing characteristics of the development and progression of both diseases include dysregulation of cell proliferation, oxidative stress, genetic changes, and inflammation. Despite conflicting data on the role of high cholesterol levels in the development of PC over the past decade, numerous studies have confirmed its importance in PC development and progression; meanwhile, statins have confirmed their value in reducing the risk of disease development and progression. The presented data confirm the need for a thorough assessment of cardiovascular risk factors, the presence of concomitant cardiovascular diseases in patients with PC, and the use of methods for the prevention and treatment of diseases associated with atherosclerosis to reduce cardiovascular risk and inhibit PC progression.https://cardiosomatics.orscience.ru/2221-7185/article/viewFile/195493/pdfatherosclerosiscardiovascular diseasecoronary heart diseaseprostate cancer |
| spellingShingle | Svetlana A. Pomeshkina Olga L. Barbarash Evgeny V. Pomeshkin Andrey I. Bragin-Maltsev Relationship between the mechanisms of atherosclerosis and prostate cancer: literature review КардиоСоматика atherosclerosis cardiovascular disease coronary heart disease prostate cancer |
| title | Relationship between the mechanisms of atherosclerosis and prostate cancer: literature review |
| title_full | Relationship between the mechanisms of atherosclerosis and prostate cancer: literature review |
| title_fullStr | Relationship between the mechanisms of atherosclerosis and prostate cancer: literature review |
| title_full_unstemmed | Relationship between the mechanisms of atherosclerosis and prostate cancer: literature review |
| title_short | Relationship between the mechanisms of atherosclerosis and prostate cancer: literature review |
| title_sort | relationship between the mechanisms of atherosclerosis and prostate cancer literature review |
| topic | atherosclerosis cardiovascular disease coronary heart disease prostate cancer |
| url | https://cardiosomatics.orscience.ru/2221-7185/article/viewFile/195493/pdf |
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