Clinical features predicting COVID-19 mortality risk

Currently, the world is involved by a pandemic of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), which has been responsible for the deaths of hundreds of thousands of people so far. The consequences of infection with SARS-CoV-2 vary widely from asymptomatic to severe. Considering the...

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Main Author: Hamidreza Kouhpayeh
Format: Article
Language:English
Published: PAGEPress Publications 2022-04-01
Series:European Journal of Translational Myology
Subjects:
Online Access:https://www.pagepressjournals.org/index.php/bam/article/view/10268
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author Hamidreza Kouhpayeh
author_facet Hamidreza Kouhpayeh
author_sort Hamidreza Kouhpayeh
collection DOAJ
description Currently, the world is involved by a pandemic of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), which has been responsible for the deaths of hundreds of thousands of people so far. The consequences of infection with SARS-CoV-2 vary widely from asymptomatic to severe. Considering the increasing prevalence of different types of virus and acute infection with this disease, strategies to prevent mortality from COVID-19 should be seriously analyzed. In this study, the epidemiological, clinical and laboratory characteristics of patients with COVID-19 were investigated in order to identify risk factors for mortality. Chronic diseases such as chronic kidney disease (CKD), COPD, diabetes, hypertension, cardiovascular disease (CVD), cancer, increased D-dimer, male gender, old age, smoking and obesity are among the deadly risk factors associated COVID-19. Furthermore, lymphopenia and neutrophilia are often present in patients with SARS-CoV-2, and the ratio of absolute neutrophils to lymphocytes (NLR) was significantly increased in patients without bacterial infection. These findings could be used in the future to control and prevent disease, because timely identification of patients with risk of COVID-19 is important to provide better treatment strategies for reduction of mortality.
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spelling doaj.art-055169a103e846298b1a5624e72a0b122022-12-22T01:17:45ZengPAGEPress PublicationsEuropean Journal of Translational Myology2037-74522037-74602022-04-0110.4081/ejtm.2022.10268Clinical features predicting COVID-19 mortality riskHamidreza Kouhpayeh0Tropical and Infectious Diseases Department, Zahedan University of Medical Sciences, Zahedan, Iran; Zahedan University of Medical Sciences Research Center, Emam Ali Hospital, Zahedan Currently, the world is involved by a pandemic of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), which has been responsible for the deaths of hundreds of thousands of people so far. The consequences of infection with SARS-CoV-2 vary widely from asymptomatic to severe. Considering the increasing prevalence of different types of virus and acute infection with this disease, strategies to prevent mortality from COVID-19 should be seriously analyzed. In this study, the epidemiological, clinical and laboratory characteristics of patients with COVID-19 were investigated in order to identify risk factors for mortality. Chronic diseases such as chronic kidney disease (CKD), COPD, diabetes, hypertension, cardiovascular disease (CVD), cancer, increased D-dimer, male gender, old age, smoking and obesity are among the deadly risk factors associated COVID-19. Furthermore, lymphopenia and neutrophilia are often present in patients with SARS-CoV-2, and the ratio of absolute neutrophils to lymphocytes (NLR) was significantly increased in patients without bacterial infection. These findings could be used in the future to control and prevent disease, because timely identification of patients with risk of COVID-19 is important to provide better treatment strategies for reduction of mortality. https://www.pagepressjournals.org/index.php/bam/article/view/10268Severe acute respiratory syndrome coronavirus 2COVID 19clinical featuresmortalityprediction
spellingShingle Hamidreza Kouhpayeh
Clinical features predicting COVID-19 mortality risk
European Journal of Translational Myology
Severe acute respiratory syndrome coronavirus 2
COVID 19
clinical features
mortality
prediction
title Clinical features predicting COVID-19 mortality risk
title_full Clinical features predicting COVID-19 mortality risk
title_fullStr Clinical features predicting COVID-19 mortality risk
title_full_unstemmed Clinical features predicting COVID-19 mortality risk
title_short Clinical features predicting COVID-19 mortality risk
title_sort clinical features predicting covid 19 mortality risk
topic Severe acute respiratory syndrome coronavirus 2
COVID 19
clinical features
mortality
prediction
url https://www.pagepressjournals.org/index.php/bam/article/view/10268
work_keys_str_mv AT hamidrezakouhpayeh clinicalfeaturespredictingcovid19mortalityrisk