Insight into Fucoidan-Based PEGylated PLGA Nanoparticles Encapsulating Methyl Anthranilic Acid: In Vitro Evaluation and In Vivo Anti-Inflammatory Study

Insight into Fucoidan-Based PEGylated PLGA Nanoparticles Encapsulating Methyl Anthranilic Acid: In Vitro Evaluation and In Vivo Anti-Inflammatory Study

A potential fucoidan-based PEGylated PLGA nanoparticles (NPs) offering a proper delivery of <i>N</i>-methyl anthranilic acid (MA, a model of hydrophobic anti-inflammatory drug) have been developed via the formation of fucoidan aqueous coating surrounding PEGylated PLGA NPs. The optimum f...

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Bibliographic Details
Main Authors: Dalia H. Abdelkader, Engy Elekhnawy, Walaa A. Negm, Thanaa A. El-Masry, May Almukainzi, Ahmed Zayed, Roland Ulber
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Marine Drugs
Subjects:
aqueous coating
cyclooxygenase-2
interleukins
reactive oxygen species
single emulsion solvent evaporation
tumor necrosis factor-alpha
Online Access:https://www.mdpi.com/1660-3397/20/11/694

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https://www.mdpi.com/1660-3397/20/11/694

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