Isolated Depo-Medrol Administration under Tenon’s Capsule for Post-COVID-19 Uveitis in a Child: A Case Report and Literature Review
Coronavirus disease 2019 (COVID-19) can manifest with ocular symptoms. These symptoms can be divided into isolated events attributed to COVID-19, and those occurring in multisystem inflammatory syndrome in children (MIS-C), a newly diagnosed disease entity associated with COVID-19 infection. Current...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-02-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/13/5/1341 |
| _version_ | 1797264271969615872 |
|---|---|
| author | Monika Modrzejewska Joanna Cyrankiewicz Oliwia Zdanowska Wiktoria Bosy-Gąsior |
| author_facet | Monika Modrzejewska Joanna Cyrankiewicz Oliwia Zdanowska Wiktoria Bosy-Gąsior |
| author_sort | Monika Modrzejewska |
| collection | DOAJ |
| description | Coronavirus disease 2019 (COVID-19) can manifest with ocular symptoms. These symptoms can be divided into isolated events attributed to COVID-19, and those occurring in multisystem inflammatory syndrome in children (MIS-C), a newly diagnosed disease entity associated with COVID-19 infection. Currently, the literature lacks specific guidelines and treatment regimens for COVID-19 ocular symptoms, especially in children. The authors present the case of a 14-and-a-half-year-old boy with bilateral uveitis of the anterior and posterior segments along with vasculitis and optic neuritis associated with SARS-CoV-2 infection. The authors also perform an up-to-date review of all available publications on the treatment of post-COVID-19 uveitis in children described in the literature between 2020 and 2023. In the case described by the authors, the treatment involved a Depo-Medrol 40 mg/mL injection uder the Tenon capsule, with two subconjunctival injections of epinephrine, topical steroid therapy and non-steroidal anti-inflammatory drugs: dexamethasone 0.1%; diclofenac eye drops. In addition, acetylsalicylic acid (150 mg) and pentoxifylline (100 mg, orally) were administered throughout the course of the disease as well as up to 12 months after its termination, until a complete improvement in visual acuity and the withdrawal of ocular lesions were achieved. It can be assumed that this type of treatment is far more beneficial for pediatric patients, with an effect comparable to systemic steroid administration with a preserved improvement in retinal-vascular circulation, without exposing the child to systemic post-steroid complications. |
| first_indexed | 2024-04-25T00:26:15Z |
| format | Article |
| id | doaj.art-055bc2b06bde413fafe2fbf1913842f5 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-04-25T00:26:15Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-055bc2b06bde413fafe2fbf1913842f52024-03-12T16:48:05ZengMDPI AGJournal of Clinical Medicine2077-03832024-02-01135134110.3390/jcm13051341Isolated Depo-Medrol Administration under Tenon’s Capsule for Post-COVID-19 Uveitis in a Child: A Case Report and Literature ReviewMonika Modrzejewska0Joanna Cyrankiewicz1Oliwia Zdanowska2Wiktoria Bosy-Gąsior3Second Chair and Department of Ophthalmology, Pomeranian Medical University in Szczecin, Al. Powstańców Wlkp. 72, 70-111 Szczecin, Poland2SP ZOZ MSWiA, ul. Jagiellońska 44, 70-382 Szczecin, PolandSzpital Uniwersytecki im. Karola Marcinkowskiego w Zielonej Górze, 65-046 Zielona Góra, PolandScientific Association of Students 2nd Department of Ophthalmology, Pomeranian Medical University in Szczecin, 70-111 Szczecin, PolandCoronavirus disease 2019 (COVID-19) can manifest with ocular symptoms. These symptoms can be divided into isolated events attributed to COVID-19, and those occurring in multisystem inflammatory syndrome in children (MIS-C), a newly diagnosed disease entity associated with COVID-19 infection. Currently, the literature lacks specific guidelines and treatment regimens for COVID-19 ocular symptoms, especially in children. The authors present the case of a 14-and-a-half-year-old boy with bilateral uveitis of the anterior and posterior segments along with vasculitis and optic neuritis associated with SARS-CoV-2 infection. The authors also perform an up-to-date review of all available publications on the treatment of post-COVID-19 uveitis in children described in the literature between 2020 and 2023. In the case described by the authors, the treatment involved a Depo-Medrol 40 mg/mL injection uder the Tenon capsule, with two subconjunctival injections of epinephrine, topical steroid therapy and non-steroidal anti-inflammatory drugs: dexamethasone 0.1%; diclofenac eye drops. In addition, acetylsalicylic acid (150 mg) and pentoxifylline (100 mg, orally) were administered throughout the course of the disease as well as up to 12 months after its termination, until a complete improvement in visual acuity and the withdrawal of ocular lesions were achieved. It can be assumed that this type of treatment is far more beneficial for pediatric patients, with an effect comparable to systemic steroid administration with a preserved improvement in retinal-vascular circulation, without exposing the child to systemic post-steroid complications.https://www.mdpi.com/2077-0383/13/5/1341panuveitispost-COVID uveitissteroid therapythromboembolic complications |
| spellingShingle | Monika Modrzejewska Joanna Cyrankiewicz Oliwia Zdanowska Wiktoria Bosy-Gąsior Isolated Depo-Medrol Administration under Tenon’s Capsule for Post-COVID-19 Uveitis in a Child: A Case Report and Literature Review Journal of Clinical Medicine panuveitis post-COVID uveitis steroid therapy thromboembolic complications |
| title | Isolated Depo-Medrol Administration under Tenon’s Capsule for Post-COVID-19 Uveitis in a Child: A Case Report and Literature Review |
| title_full | Isolated Depo-Medrol Administration under Tenon’s Capsule for Post-COVID-19 Uveitis in a Child: A Case Report and Literature Review |
| title_fullStr | Isolated Depo-Medrol Administration under Tenon’s Capsule for Post-COVID-19 Uveitis in a Child: A Case Report and Literature Review |
| title_full_unstemmed | Isolated Depo-Medrol Administration under Tenon’s Capsule for Post-COVID-19 Uveitis in a Child: A Case Report and Literature Review |
| title_short | Isolated Depo-Medrol Administration under Tenon’s Capsule for Post-COVID-19 Uveitis in a Child: A Case Report and Literature Review |
| title_sort | isolated depo medrol administration under tenon s capsule for post covid 19 uveitis in a child a case report and literature review |
| topic | panuveitis post-COVID uveitis steroid therapy thromboembolic complications |
| url | https://www.mdpi.com/2077-0383/13/5/1341 |
| work_keys_str_mv | AT monikamodrzejewska isolateddepomedroladministrationundertenonscapsuleforpostcovid19uveitisinachildacasereportandliteraturereview AT joannacyrankiewicz isolateddepomedroladministrationundertenonscapsuleforpostcovid19uveitisinachildacasereportandliteraturereview AT oliwiazdanowska isolateddepomedroladministrationundertenonscapsuleforpostcovid19uveitisinachildacasereportandliteraturereview AT wiktoriabosygasior isolateddepomedroladministrationundertenonscapsuleforpostcovid19uveitisinachildacasereportandliteraturereview |