Effects of GLP-1 Receptor Agonists on Biological Behavior of Colorectal Cancer Cells by Regulating PI3K/AKT/mTOR Signaling Pathway

Effects of GLP-1 Receptor Agonists on Biological Behavior of Colorectal Cancer Cells by Regulating PI3K/AKT/mTOR Signaling Pathway

Colorectal cancer (CRC) has become one of the top ten malignant tumors with a high incidence rate and mortality. Due to the lack of a good CRC screening program, most of the CRC patients are being transferred at the time of treatment. The conventional treatment cannot effectively improve the prognos...

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Bibliographic Details
Main Authors: Guoxiang Tong, Tianhao Peng, Ya Chen, Lijuan Sha, Huikang Dai, Yidong Xiang, Zhiqi Zou, Heli He, Sha Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
colorectal cancer
GLP-1 receptor agonist
liraglutide
PI3K/AKT/mTOR
migration
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.901559/full

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