Fibrinogen Degradation Products and D-Dimers in Patients with Breast Carcinoma

Background: Many patients with cancer are complicated by disseminated intravascular coagulation. This study was aimed to determine the level of Fibrinogen Degradation Products and D-Dimers at various stages in patients suffering from breast carcinoma. Material and methods: This was a cross-section...

Full description

Bibliographic Details
Main Authors: Malik Zeb Khan, Muhammad Shoaib Khan, Fazle Raziq, Aziz Marjan Khattak
Format: Article
Language:English
Published: Gomal Medical College, D.I.Khan, Pakistan 2007-06-01
Series:Gomal Journal of Medical Sciences
Online Access:http://gjms.com.pk/ojs24/index.php/gjms/article/view/95
_version_ 1819069577814867968
author Malik Zeb Khan
Muhammad Shoaib Khan
Fazle Raziq
Aziz Marjan Khattak
author_facet Malik Zeb Khan
Muhammad Shoaib Khan
Fazle Raziq
Aziz Marjan Khattak
author_sort Malik Zeb Khan
collection DOAJ
description Background: Many patients with cancer are complicated by disseminated intravascular coagulation. This study was aimed to determine the level of Fibrinogen Degradation Products and D-Dimers at various stages in patients suffering from breast carcinoma. Material and methods: This was a cross-sectional study conducted in the Department of Pathology, Postgraduate Medical Institute, Lahore, Pakistan, from June 2003 to June 2004. Sampling method was by convenience. Two groups were taken; Group-1 including 50 patients with breast carcinoma and Group-2 comprising of 25 healthy controls. Fibrinogen Degradation Products and D-Dimer levels were estimated in the blood and the results compared. Results: Out of 50 patients, 28 (56%) had Fibrinogen Degradation Products >40 μg/ml; 13 (26%) in stageIII and 15 (30%) in stage-IV. 15 (30%) patients had levels between 5-40μg/ml; 8 (16%) in stage-II and 7 (14%) in stage-III. Only 7 (14%) had levels
first_indexed 2024-12-21T16:52:16Z
format Article
id doaj.art-055da85f13554662bd2cd83dfd49a385
institution Directory Open Access Journal
issn 1819-7973
1997-2067
language English
last_indexed 2024-12-21T16:52:16Z
publishDate 2007-06-01
publisher Gomal Medical College, D.I.Khan, Pakistan
record_format Article
series Gomal Journal of Medical Sciences
spelling doaj.art-055da85f13554662bd2cd83dfd49a3852022-12-21T18:56:50ZengGomal Medical College, D.I.Khan, PakistanGomal Journal of Medical Sciences1819-79731997-20672007-06-015195Fibrinogen Degradation Products and D-Dimers in Patients with Breast CarcinomaMalik Zeb KhanMuhammad Shoaib KhanFazle RaziqAziz Marjan KhattakBackground: Many patients with cancer are complicated by disseminated intravascular coagulation. This study was aimed to determine the level of Fibrinogen Degradation Products and D-Dimers at various stages in patients suffering from breast carcinoma. Material and methods: This was a cross-sectional study conducted in the Department of Pathology, Postgraduate Medical Institute, Lahore, Pakistan, from June 2003 to June 2004. Sampling method was by convenience. Two groups were taken; Group-1 including 50 patients with breast carcinoma and Group-2 comprising of 25 healthy controls. Fibrinogen Degradation Products and D-Dimer levels were estimated in the blood and the results compared. Results: Out of 50 patients, 28 (56%) had Fibrinogen Degradation Products >40 μg/ml; 13 (26%) in stageIII and 15 (30%) in stage-IV. 15 (30%) patients had levels between 5-40μg/ml; 8 (16%) in stage-II and 7 (14%) in stage-III. Only 7 (14%) had levelshttp://gjms.com.pk/ojs24/index.php/gjms/article/view/95
spellingShingle Malik Zeb Khan
Muhammad Shoaib Khan
Fazle Raziq
Aziz Marjan Khattak
Fibrinogen Degradation Products and D-Dimers in Patients with Breast Carcinoma
Gomal Journal of Medical Sciences
title Fibrinogen Degradation Products and D-Dimers in Patients with Breast Carcinoma
title_full Fibrinogen Degradation Products and D-Dimers in Patients with Breast Carcinoma
title_fullStr Fibrinogen Degradation Products and D-Dimers in Patients with Breast Carcinoma
title_full_unstemmed Fibrinogen Degradation Products and D-Dimers in Patients with Breast Carcinoma
title_short Fibrinogen Degradation Products and D-Dimers in Patients with Breast Carcinoma
title_sort fibrinogen degradation products and d dimers in patients with breast carcinoma
url http://gjms.com.pk/ojs24/index.php/gjms/article/view/95
work_keys_str_mv AT malikzebkhan fibrinogendegradationproductsandddimersinpatientswithbreastcarcinoma
AT muhammadshoaibkhan fibrinogendegradationproductsandddimersinpatientswithbreastcarcinoma
AT fazleraziq fibrinogendegradationproductsandddimersinpatientswithbreastcarcinoma
AT azizmarjankhattak fibrinogendegradationproductsandddimersinpatientswithbreastcarcinoma