Unique characteristics of CpG island methylator phenotype (CIMP) in a Chinese population with colorectal cancer

Unique characteristics of CpG island methylator phenotype (CIMP) in a Chinese population with colorectal cancer

Abstract Background Molecular characteristics of CpG island methylator phenotype (CIMP) in colorectal cancer (CRC) have been well documented in Western, but not in Chinese, populations. Methods We investigated the incidence of CIMP, BRAF/KRAS mutation, and microsatellite instability (MSI) in a Chine...

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Bibliographic Details
Main Authors: Jiang Liu, Li Tang, Jinhua Yi, Guimei Li, Youwang Lu, Yu Xu, Shuhua Zhao, Rui Mao, Xiaolu Li, Li Ren, Kunhua Wang
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Gastroenterology
Subjects:
Colorectal cancer
CpG island methylator phenotype
CIMP
BRAF mutations
KRAS mutations
Online Access:http://link.springer.com/article/10.1186/s12876-019-1086-x

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