Clinical case: severe course of adenoviral conjunctivitis with a hemorrhagic component complicated by a toxic-allergic reaction against a pregnancy

One of the manifestations of adenovirus keratoconjunctivitis extensive subconjunctival hemorrhages is the characteristic of rather rare hemorrhagic form of conjunctivitis of severe course. Patients, especially pregnant women, with clinical manifestations of adenoviral conjunctivitis of severe cour...

Full description

Bibliographic Details
Main Authors: V. N. Trubilin, E. G. Poluninа, D. V. Andzhelova, E. A. Kasparova, Yu. V. Evstigneeva
Format: Article
Language:English
Published: Eco-vector 2018-12-01
Series:Клиническая практика
Subjects:
Online Access:https://journals.eco-vector.com/clinpractice/article/viewFile/10777/8460
_version_ 1797710941769433088
author V. N. Trubilin
E. G. Poluninа
D. V. Andzhelova
E. A. Kasparova
Yu. V. Evstigneeva
author_facet V. N. Trubilin
E. G. Poluninа
D. V. Andzhelova
E. A. Kasparova
Yu. V. Evstigneeva
author_sort V. N. Trubilin
collection DOAJ
description One of the manifestations of adenovirus keratoconjunctivitis extensive subconjunctival hemorrhages is the characteristic of rather rare hemorrhagic form of conjunctivitis of severe course. Patients, especially pregnant women, with clinical manifestations of adenoviral conjunctivitis of severe course with a hemorrhagic component complicated by a toxic-allergic reaction, require close attention not only from ophthalmologists. It is necessary to conduct a comprehensive examination, including: general blood test, coagulogram, consultation of the therapist. Clinical signs of deterioration, in the early days of the disease, against the backdrop of treatment, is a clinical feature of the course of adenovirus infection, which should be informed to the patient. The use of a complex approach using the domestic non-toxic inducer of interferon formation of Poludan (polyA:polyU complex) in instillations and injections, supplemented by scraping-massage with a glass rod of the tarsal conjunctiva, facilitating the elimination of adenovirus from conjunctival follicles, quickly and effectively reversed the phenomenon of severe AVC. The appointment of corticosteroid therapy, regardless of the severity of the toxic-allergic reaction, is shown no earlier than 7 days after the manifestation of the disease.
first_indexed 2024-03-12T06:59:37Z
format Article
id doaj.art-055e2adb24cd4edf802823e3cded4762
institution Directory Open Access Journal
issn 2220-3095
2618-8627
language English
last_indexed 2024-03-12T06:59:37Z
publishDate 2018-12-01
publisher Eco-vector
record_format Article
series Клиническая практика
spelling doaj.art-055e2adb24cd4edf802823e3cded47622023-09-02T23:46:17ZengEco-vectorКлиническая практика2220-30952618-86272018-12-0191768110.17816/clinpract09176-819726Clinical case: severe course of adenoviral conjunctivitis with a hemorrhagic component complicated by a toxic-allergic reaction against a pregnancyV. N. Trubilin0E. G. Poluninа1D. V. Andzhelova2E. A. Kasparova3Yu. V. Evstigneeva4Federal institute of the professional developmentFederal institute of the professional developmentResearch Institute of Eye DiseasesResearch Institute of Eye DiseasesOphthalmology Clinic of Dr. KurenkovOne of the manifestations of adenovirus keratoconjunctivitis extensive subconjunctival hemorrhages is the characteristic of rather rare hemorrhagic form of conjunctivitis of severe course. Patients, especially pregnant women, with clinical manifestations of adenoviral conjunctivitis of severe course with a hemorrhagic component complicated by a toxic-allergic reaction, require close attention not only from ophthalmologists. It is necessary to conduct a comprehensive examination, including: general blood test, coagulogram, consultation of the therapist. Clinical signs of deterioration, in the early days of the disease, against the backdrop of treatment, is a clinical feature of the course of adenovirus infection, which should be informed to the patient. The use of a complex approach using the domestic non-toxic inducer of interferon formation of Poludan (polyA:polyU complex) in instillations and injections, supplemented by scraping-massage with a glass rod of the tarsal conjunctiva, facilitating the elimination of adenovirus from conjunctival follicles, quickly and effectively reversed the phenomenon of severe AVC. The appointment of corticosteroid therapy, regardless of the severity of the toxic-allergic reaction, is shown no earlier than 7 days after the manifestation of the disease.https://journals.eco-vector.com/clinpractice/article/viewFile/10777/8460adenovirus keratoconjunctivitispregnancypoludan
spellingShingle V. N. Trubilin
E. G. Poluninа
D. V. Andzhelova
E. A. Kasparova
Yu. V. Evstigneeva
Clinical case: severe course of adenoviral conjunctivitis with a hemorrhagic component complicated by a toxic-allergic reaction against a pregnancy
Клиническая практика
adenovirus keratoconjunctivitis
pregnancy
poludan
title Clinical case: severe course of adenoviral conjunctivitis with a hemorrhagic component complicated by a toxic-allergic reaction against a pregnancy
title_full Clinical case: severe course of adenoviral conjunctivitis with a hemorrhagic component complicated by a toxic-allergic reaction against a pregnancy
title_fullStr Clinical case: severe course of adenoviral conjunctivitis with a hemorrhagic component complicated by a toxic-allergic reaction against a pregnancy
title_full_unstemmed Clinical case: severe course of adenoviral conjunctivitis with a hemorrhagic component complicated by a toxic-allergic reaction against a pregnancy
title_short Clinical case: severe course of adenoviral conjunctivitis with a hemorrhagic component complicated by a toxic-allergic reaction against a pregnancy
title_sort clinical case severe course of adenoviral conjunctivitis with a hemorrhagic component complicated by a toxic allergic reaction against a pregnancy
topic adenovirus keratoconjunctivitis
pregnancy
poludan
url https://journals.eco-vector.com/clinpractice/article/viewFile/10777/8460
work_keys_str_mv AT vntrubilin clinicalcaseseverecourseofadenoviralconjunctivitiswithahemorrhagiccomponentcomplicatedbyatoxicallergicreactionagainstapregnancy
AT egpolunina clinicalcaseseverecourseofadenoviralconjunctivitiswithahemorrhagiccomponentcomplicatedbyatoxicallergicreactionagainstapregnancy
AT dvandzhelova clinicalcaseseverecourseofadenoviralconjunctivitiswithahemorrhagiccomponentcomplicatedbyatoxicallergicreactionagainstapregnancy
AT eakasparova clinicalcaseseverecourseofadenoviralconjunctivitiswithahemorrhagiccomponentcomplicatedbyatoxicallergicreactionagainstapregnancy
AT yuvevstigneeva clinicalcaseseverecourseofadenoviralconjunctivitiswithahemorrhagiccomponentcomplicatedbyatoxicallergicreactionagainstapregnancy