Gas chromatography mass spectrometry analysis and larvicidal activity of leaf essential oil extract of Leucas aspera against dengue, malaria and filariasis vectors
Abstract Background Insect-transmitted diseases cause high morbidity but they also include deadly diseases that cause high mortality rates among infected individuals. Several mosquito species including Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus are vectors. Ae. aegypti, a vector...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2018-11-01
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| Series: | Journal of Basic and Applied Zoology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41936-018-0064-0 |
| _version_ | 1819108259671310336 |
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| author | Devan Elumalai Manikandan Kayalvizhi Patheri Kunil Kaleena Anandhan Vignesh Maduraiveeran Hemavathi |
| author_facet | Devan Elumalai Manikandan Kayalvizhi Patheri Kunil Kaleena Anandhan Vignesh Maduraiveeran Hemavathi |
| author_sort | Devan Elumalai |
| collection | DOAJ |
| description | Abstract Background Insect-transmitted diseases cause high morbidity but they also include deadly diseases that cause high mortality rates among infected individuals. Several mosquito species including Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus are vectors. Ae. aegypti, a vector of yellow fever, dengue, and chikungunya is widely distributed in the tropical and subtropical zones. An. stephensi is the primary vector of malaria in India and other west Asian countries. C. quinquefasciatus is a vector of lymphatic filariasis and it is widely distributed tropical diseases with around 120 million people infected worldwide. Results In the view of an increasing interest in developing plant-derived insecticides as an alternative to chemical insecticides, this study was undertaken to assess the larvicidal potential of essential oil extracted from Leucas aspera leaves against three medically important species of mosquito vectors, Ae. aegypti, An. stephensi, and C. quinquefasciatus. The oil extract was found to be potent against Ae. Aegypti LC50 and LC90 (lethal concentration LC) value of 15.59 ppm and 46.77 ppm when compared to An. stephensi (17.10 ppm and 51.20 ppm) and C. quinquefasciatus with LC50 and LC90 (16.19 ppm and 47.79 ppm) respectively. Gas chromatography mass spectrometry analysis of the essential oil extract of L. aspera was done to identify the major phytocompounds. Conclusion The results showed that the oil extract of L. aspera and its effective constituents can be considered as potent source for the production of natural larvicides. |
| first_indexed | 2024-12-22T03:07:05Z |
| format | Article |
| id | doaj.art-056002e22f954351b90437b9c97cd31e |
| institution | Directory Open Access Journal |
| issn | 2090-990X |
| language | English |
| last_indexed | 2024-12-22T03:07:05Z |
| publishDate | 2018-11-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Journal of Basic and Applied Zoology |
| spelling | doaj.art-056002e22f954351b90437b9c97cd31e2022-12-21T18:41:01ZengSpringerOpenJournal of Basic and Applied Zoology2090-990X2018-11-017911710.1186/s41936-018-0064-0Gas chromatography mass spectrometry analysis and larvicidal activity of leaf essential oil extract of Leucas aspera against dengue, malaria and filariasis vectorsDevan Elumalai0Manikandan Kayalvizhi1Patheri Kunil Kaleena2Anandhan Vignesh3Maduraiveeran Hemavathi4Department of Zoology, Pachaiyappas College For MenDepartment of Zoology, Pachaiyappas College For MenDepartment of Zoology, Presidency College (Autonomous)Department of Botany, Pachaiyappas College For MenDepartment of Zoology, Pachaiyappas College For WomenAbstract Background Insect-transmitted diseases cause high morbidity but they also include deadly diseases that cause high mortality rates among infected individuals. Several mosquito species including Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus are vectors. Ae. aegypti, a vector of yellow fever, dengue, and chikungunya is widely distributed in the tropical and subtropical zones. An. stephensi is the primary vector of malaria in India and other west Asian countries. C. quinquefasciatus is a vector of lymphatic filariasis and it is widely distributed tropical diseases with around 120 million people infected worldwide. Results In the view of an increasing interest in developing plant-derived insecticides as an alternative to chemical insecticides, this study was undertaken to assess the larvicidal potential of essential oil extracted from Leucas aspera leaves against three medically important species of mosquito vectors, Ae. aegypti, An. stephensi, and C. quinquefasciatus. The oil extract was found to be potent against Ae. Aegypti LC50 and LC90 (lethal concentration LC) value of 15.59 ppm and 46.77 ppm when compared to An. stephensi (17.10 ppm and 51.20 ppm) and C. quinquefasciatus with LC50 and LC90 (16.19 ppm and 47.79 ppm) respectively. Gas chromatography mass spectrometry analysis of the essential oil extract of L. aspera was done to identify the major phytocompounds. Conclusion The results showed that the oil extract of L. aspera and its effective constituents can be considered as potent source for the production of natural larvicides.http://link.springer.com/article/10.1186/s41936-018-0064-0Vector controlL. asperaGC-MSAe. aegyptiAn. stephensi and C. quinquefasciatus |
| spellingShingle | Devan Elumalai Manikandan Kayalvizhi Patheri Kunil Kaleena Anandhan Vignesh Maduraiveeran Hemavathi Gas chromatography mass spectrometry analysis and larvicidal activity of leaf essential oil extract of Leucas aspera against dengue, malaria and filariasis vectors Journal of Basic and Applied Zoology Vector control L. aspera GC-MS Ae. aegypti An. stephensi and C. quinquefasciatus |
| title | Gas chromatography mass spectrometry analysis and larvicidal activity of leaf essential oil extract of Leucas aspera against dengue, malaria and filariasis vectors |
| title_full | Gas chromatography mass spectrometry analysis and larvicidal activity of leaf essential oil extract of Leucas aspera against dengue, malaria and filariasis vectors |
| title_fullStr | Gas chromatography mass spectrometry analysis and larvicidal activity of leaf essential oil extract of Leucas aspera against dengue, malaria and filariasis vectors |
| title_full_unstemmed | Gas chromatography mass spectrometry analysis and larvicidal activity of leaf essential oil extract of Leucas aspera against dengue, malaria and filariasis vectors |
| title_short | Gas chromatography mass spectrometry analysis and larvicidal activity of leaf essential oil extract of Leucas aspera against dengue, malaria and filariasis vectors |
| title_sort | gas chromatography mass spectrometry analysis and larvicidal activity of leaf essential oil extract of leucas aspera against dengue malaria and filariasis vectors |
| topic | Vector control L. aspera GC-MS Ae. aegypti An. stephensi and C. quinquefasciatus |
| url | http://link.springer.com/article/10.1186/s41936-018-0064-0 |
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